Interleukin 33 Antikörper (IL33) (AA 109-266)

Details for Product anti-IL33 Antibody No. ABIN4899216, Anbieter: Anmelden zum Anzeigen
Antigen
  • IL33
  • C9orf26
  • DVS27
  • IL1F11
  • NF-HEV
  • NFEHEV
  • RP11-575C20.2
  • 9230117N10Rik
  • Il-33
  • Il1f11
  • RGD1311155
  • interleukin 33
  • IL33
  • Il33
Epitop
AA 109-266
70
26
20
14
12
7
6
5
5
4
3
3
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
Reaktivität
Maus
292
106
48
8
4
3
2
2
Wirt
Ziege
191
133
23
23
4
3
2
1
1
Klonalität
Polyklonal
Konjugat
Dieser Interleukin 33 Antikörper ist unkonjugiert
36
19
14
14
8
7
5
5
5
4
4
4
3
3
3
3
3
3
3
3
3
3
1
1
1
1
1
1
1
Applikation
Cytometry by Time of Flight (CyTOF), ELISA (Capture), Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunohistochemistry (IHC), Neutralization (Neut), Western Blotting (WB)
281
216
89
60
45
23
21
20
16
14
13
11
7
5
5
4
3
3
2
2
2
1
1
Optionen
Hersteller
Anmelden zum Anzeigen
Hersteller Produkt- Nr.
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Immunogen E. coli-derived recombinant mouse IL-33, Ser109-Ile266, Accession # Q8BVZ5
Isotyp IgG
Spezifität Detects mouse IL-33 in ELISAs and Western blots. In sandwich immunoassays, less than 2 % cross-reactivity with recombinant human IL-33 is observed.
Reinigung Antigen Affinity-purified
Sterilität 0.2 μm filtered
Endotoxin-Niveau <0.10 EU per 1 μg of the antibody by the LAL method.
Andere Bezeichnung IL-33 (IL33 Antibody Abstract)
Hintergrund Alternative Names: C9orf26, C9orf26chromosome 9 open reading frame 26 (NF-HEV), DKFZp586H0523, DVS27, DVS27-related protein, IL1F11, IL-1F11, IL33, IL-33, interleukin 33, Interleukin-1 family member 11, interleukin-33, NFHEV, NF-HEV, NF-HEVNFEHEV, Nuclear factor from high endothelial venules, RP11-575C20.2
Gen-ID 90865
UniProt Q8BVZ5
Forschungsgebiet Angiogenesis, Cytokines, Cardiovascular, Innate Immunity, Hormones, Hypertrophy
Pathways Production of Molecular Mediator of Immune Response
Applikationshinweise Western Blot 0.4 μg/mL
Immunohistochemistry 5-15 μg/mL
Neutralization 10-50 ng/mL
Intracellular Staining by Flow Cytometry 2.5 μg/10^6 cells
Immunocytochemistry 5-15 μg/mL
CyTOF-ready
ELISA Capture (Matched Antibody Pair) 0.2-0.8 μg/mL
Beschränkungen Nur für Forschungszwecke einsetzbar
Rekonstitution Reconstitute at 0.2 mg/mL in sterile PBS.
Buffer Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose.
Konservierungsmittel Without preservative
Lagerung 4 °C,-20 °C,-80 °C
Informationen zur Lagerung Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt,-20°C to -70°C as supplied. 1 month,2°C to 8°C under sterile conditions after reconstitution. 6 months,-20°C to -70°C under sterile conditions after reconstitution.
Haltbarkeit 12 months
Bilder des Herstellers
Neutralization (Neut) image for anti-Interleukin 33 (IL33) (AA 109-266) antibody (ABIN4899216) Proliferation Induced by IL-33 and Neutralization by Human IL-33 Antibody. Recombinan...
ELISA image for anti-Interleukin 33 (IL33) (AA 109-266) antibody (ABIN4899216) IL-33 in Mouse Spleen. IL-33 was detected in immersion fixed frozen sections of mouse...
Flow Cytometry (FACS) image for anti-Interleukin 33 (IL33) (AA 109-266) antibody (ABIN4899216) Detection of IL-33 in Mouse Splenocytes by Flow Cytometry. Mouse splenocytes were tre...
Western Blotting (WB) image for anti-Interleukin 33 (IL33) (AA 109-266) antibody (ABIN4899216) Detection of Mouse IL-33 by Western Blot. Western blot shows lysates of HEK293T human...
Immunocytochemistry (ICC) image for anti-Interleukin 33 (IL33) (AA 109-266) antibody (ABIN4899216) IL-33 in bEnd.3 Mouse Cell Line. IL-33 was detected in immersion fixed bEnd.3 mouse e...
Produkt verwendet in: Athari, Poirier, Biton, Semerano, Hervé, Raffaillac, Lemeiter, Herbelin, Girard, Caux, Boissier, Bessis: "Collagen-induced arthritis and imiquimod-induced psoriasis develop independently of interleukin-33." in: Arthritis research & therapy, Vol. 18, Issue 1, pp. 143, 2016 (PubMed). Von den Autoren verwendete Methode: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (Probematerial (Species): Mouse (Murine)).

Mahmutovic Persson, Akbarshahi, Menzel, Brandelius, Uller: "Increased expression of upstream TH2-cytokines in a mouse model of viral-induced asthma exacerbation." in: Journal of translational medicine, Vol. 14, pp. 52, 2016 (PubMed). Von den Autoren verwendete Methode: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (Probematerial (Species): Mouse (Murine)).

Aguiniga, Yaggie, Schaeffer, Klumpp: "Lipopolysaccharide Domains Modulate Urovirulence." in: Infection and immunity, Vol. 84, Issue 11, pp. 3131-3140, 2016 (PubMed). Von den Autoren verwendete Methode: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (Probematerial (Species): Mouse (Murine)).

Liu, Tai, Achanta, Kaelberer, Caceres, Shao, Fang, Jordt: "IL-33/ST2 signaling excites sensory neurons and mediates itch response in a mouse model of poison ivy contact allergy." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 113, Issue 47, pp. E7572-E7579, 2016 (PubMed). Von den Autoren verwendete Methode: In vivo Studies (in vivo) (Probematerial (Species): Mouse (Murine)).

Denney, Byrne, Shea, Buckley, Pease, Herledan, Walker, Gregory, Lloyd: "Pulmonary Epithelial Cell-Derived Cytokine TGF-β1 Is a Critical Cofactor for Enhanced Innate Lymphoid Cell Function." in: Immunity, Vol. 43, Issue 5, pp. 945-58, 2015 (PubMed). Von den Autoren verwendete Methode: ELISA (Capture) (ELISA (Capture)) (Probematerial (Species): Mouse (Murine)).

Kim, Morita, Kobayashi, Eisenbarth, Lee, Elias, Eynon, Flavell: "AMCase is a crucial regulator of type 2 immune responses to inhaled house dust mites." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 112, Issue 22, pp. E2891-9, 2015 (PubMed). Von den Autoren verwendete Methode: ELISA (Capture) (ELISA (Capture)) (Probematerial (Species): Mouse (Murine)).

Palomo, Reverchon, Piotet, Besnard, Couturier-Maillard, Maillet, Tefit, Erard, Mazier, Ryffel, Quesniaux: "Critical role of IL-33 receptor ST2 in experimental cerebral malaria development." in: European journal of immunology, Vol. 45, Issue 5, pp. 1354-65, 2015 (PubMed). Von den Autoren verwendete Methode: Immunohistochemistry (Frozen Sections) (IHC (fro)) (Probematerial (Species): Mouse (Murine)).

Mager, Riether, Schürch, Banz, Wasmer, Stuber, Theocharides, Li, Xia, Saito, Nakae, Baerlocher, Manz, McCoy, Macpherson, Ochsenbein, Beutler, Krebs: "IL-33 signaling contributes to the pathogenesis of myeloproliferative neoplasms." in: The Journal of clinical investigation, Vol. 125, Issue 7, pp. 2579-91, 2015 (PubMed). Von den Autoren verwendete Methode: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (Probematerial (Species): Mouse (Murine)).

Sundnes, Pietka, Loos, Sponheim, Rankin, Pflanz, Bertelsen, Sitek, Hol, Haraldsen, Khnykin: "Epidermal Expression and Regulation of Interleukin-33 during Homeostasis and Inflammation: Strong Species Differences." in: The Journal of investigative dermatology, Vol. 135, Issue 7, pp. 1771-80, 2015 (PubMed). Von den Autoren verwendete Methode: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (Probematerial (Species): Human).

Millar, Gilchrist, Akbar, Reilly, Kerr, Campbell, Murrell, Liew, Kurowska-Stolarska, McInnes: "MicroRNA29a regulates IL-33-mediated tissue remodelling in tendon disease." in: Nature communications, Vol. 6, pp. 6774, 2015 (PubMed). Von den Autoren verwendete Methode: In vivo Studies (in vivo) (Probematerial (Species): Mouse (Murine)).

Liu, Kanaoka, Barrett, Feng, Garofalo, Lai, Buchheit, Bhattacharya, Laidlaw, Katz, Boyce: "Aspirin-Exacerbated Respiratory Disease Involves a Cysteinyl Leukotriene-Driven IL-33-Mediated Mast Cell Activation Pathway." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 195, Issue 8, pp. 3537-45, 2015 (PubMed). Von den Autoren verwendete Methode: Neutralization (Neut) (Probematerial (Species): Mouse (Murine)).

Bu, Zhang, Wang, Ren, Wen: "IL-33 reflects dynamics of disease activity in patients with autoimmune hemolytic anemia by regulating autoantibody production." in: Journal of translational medicine, Vol. 13, pp. 381, 2015 (PubMed). Von den Autoren verwendete Methode: Neutralization (Neut) (Probematerial (Species): Mouse (Murine)).

Polumuri, Jayakar, Shirey, Roberts, Perkins, Pitha, Vogel: "Transcriptional regulation of murine IL-33 by TLR and non-TLR agonists." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 189, Issue 1, pp. 50-60, 2012 (PubMed). Von den Autoren verwendete Methode: Flow Cytometry (FACS) (Probematerial (Species): Mouse (Murine)).

Paulissen, El Hour, Rocks, Guéders, Bureau, Foidart, Lopez-Otin, Noel, Cataldo: "Control of allergen-induced inflammation and hyperresponsiveness by the metalloproteinase ADAMTS-12." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 189, Issue 8, pp. 4135-43, 2012 (PubMed). Von den Autoren verwendete Methode: Immunohistochemistry (IHC) (Probematerial (Species): Mouse (Murine)).

Nelson, Christmann, Werner, Metz, Trevor, Lowell, Steele: "IL-33 and M2a alveolar macrophages promote lung defense against the atypical fungal pathogen Pneumocystis murina." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 186, Issue 4, pp. 2372-81, 2011 (PubMed). Von den Autoren verwendete Methode: Immunohistochemistry (Frozen Sections) (IHC (fro)) (Probematerial (Species): Mouse (Murine)).

Byrne, Beaugie, OSullivan, Leighton, Halliday: "The immune-modulating cytokine and endogenous Alarmin interleukin-33 is upregulated in skin exposed to inflammatory UVB radiation." in: The American journal of pathology, Vol. 179, Issue 1, pp. 211-22, 2011 (PubMed). Von den Autoren verwendete Methode: In vivo Studies (in vivo) (Probematerial (Species): Mouse (Murine)).

Ohno, Oboki, Morita, Kajiwara, Arae, Tanaka, Ikeda, Iikura, Akiyama, Inoue, Matsumoto, Sudo, Azuma, Okumura, Kamradt, Saito, Nakae: "Paracrine IL-33 stimulation enhances lipopolysaccharide-mediated macrophage activation." in: PLoS ONE, Vol. 6, Issue 4, pp. e18404, 2011 (PubMed). Von den Autoren verwendete Methode: Neutralization (Neut) (Probematerial (Species): Mouse (Murine)).

Enoksson, Lyberg, Möller-Westerberg, Fallon, Nilsson, Lunderius-Andersson: "Mast cells as sensors of cell injury through IL-33 recognition." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 186, Issue 4, pp. 2523-8, 2011 (PubMed). Von den Autoren verwendete Methode: Western Blotting (WB) (Probematerial (Species): Mouse (Murine)).

Hazlett, McClellan, Barrett, Huang, Zhang, Wu, van Rooijen, Szliter: "IL-33 shifts macrophage polarization, promoting resistance against Pseudomonas aeruginosa keratitis." in: Investigative ophthalmology & visual science, Vol. 51, Issue 3, pp. 1524-32, 2010 (PubMed). Von den Autoren verwendete Methode: Immunohistochemistry (Frozen Sections) (IHC (fro)) (Probematerial (Species): Mouse (Murine)).

Ohno, Oboki, Kajiwara, Morii, Aozasa, Flavell, Okumura, Saito, Nakae: "Caspase-1, caspase-8, and calpain are dispensable for IL-33 release by macrophages." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 183, Issue 12, pp. 7890-7, 2009 (PubMed). Von den Autoren verwendete Methode: ELISA (ELISA) (Probematerial (Species): Mouse (Murine)).

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