»
Antikörper
»
anti-Interleukin 1, beta (IL1B) Antikörper
Interleukin 1, beta (IL1B) Antikörper
| Antigen |
|
| Synonyme |
IL-1, IL1F2, IL1-BETA, IL1B, IL-1BETA, MGC111873, zgc:111873, IL-1B |
| Klonalität |
Monoklonal (B122) |
|
Wirt
|
|
|
Reaktivität
|
|
|
Applikation
|
Alternativen Immunhistochemie (IHC), Western Blot (WB), Immunhistochemie (Paraffinschnitte) (IHC (p)), Immunpräzipitation (IP)
Western Blot (WB) (90), Enzyme Immunoassay (EIA) (71), ELISA (41), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (23), Immunhistochemie (IHC) (16), Durchflusszytometrie (FACS) (15), Funktionale Studien (Func) (14), Immunpräzipitation (IP) (13), Immunfluoreszenz (IF) (11), ELISA (Fangantikörper) (10), Neutralisierung (Neut) (10), ELISA (Detektionsantikörper) (9), Immunhistochemie (Paraffinschnitte) (IHC (p)) (7), Intrazelluläre Durchflusszytometrie (ICFC) (7), Dot Blot (Dot) (6), Radioimmunoassay (RIA) (4), ELISPOT (Detektionsantikörper) (3), ELISPOT (Fangantikörper) (2), Blockierende Antikörper (Inhibition) (1), Immunzytochemie (ICC) (1), Intrazellulärfärbung (IS) (1)
|
| Produktnummer |
ABIN488773 |
| Menge |
50 µg (0.1 mg/ml) |
| Preis |
105,13 € Zzgl. Versandkosten €20,00 und MWSt
|
| Lieferung nach |
|
| Verfügbarkeit |
Lieferung in 3 bis 10 Werktagen |
|
Weitere Bezeichnung
|
IL-1beta
|
|
Isotyp
|
IgG (Passende Sekundärantikörper)
|
|
Klon
|
B122
|
|
Beschreibung
|
Interleukin 1 beta (IL1 beta) is a proinflammatory cytokine belonging to IL1 family that is synthesized as a precursor. The IL1 beta precursor form is not biologically active. It is expressed mainly by stimulated macrophages and monocytes.1,2 IL1 beta is known to be a mediator in inflammatory response and to be involved in a variety of cellular activities, proliferation, differentiation and apoptosis. It has been recently found that IL1 beta is a major cause of severe inflammation in the mouse model of Crohns disease which makes IL1 beta an important target for this disease.3
|
|
Spezifität
|
Anti-Mouse IL-1 (Clone B122) recognizes Mouse IL-1. This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
|
|
Applikationshinweise
|
IHC (NBF/Par.), IP, WB. Each Investigator should determine their own optimal working dilution for specific applications.
|
|
Konzentration
|
0.1 mg/ml
|
|
Reinigung
|
Purified
|
|
Buffer
|
This purified antibody is formulated in 0.01 M phosphate buffered saline (PBS) pH 7.4, 150 mM NaCl, 1% BSA and 0.09% sodium azide as a preservative. Storage and Stability This antibody is stable for at least one week when stored at 2-8C. For long term sto
|
|
Lagerung
|
This antibody is stable for at least one week when stored at 2-8°C. For long term storage, aliquot in working volumes without diluting and store at 20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
|
|
Beschränkungen
|
Nur für Forschungszwecke einsetzbar
|
Alternativen zu Antigen "Interleukin 1, beta (IL1B)", Typ "Antikörper" finden
|
Wirte
|
Maus (86), Kaninchen (68), Ziege (5), Hamster (4), Ratte (4), Schaf (2), Huhn (1)
|
|
Reaktivitäten
|
Human (110), Maus (29), Ratte (Rattus) (21), Rind (Kuh) (6), Schaf (5), Affe (4), Ziege (2), Schwein (2), Huhn (1), Kaninchen (1)
|
|
Applikationen
|
Western Blot (WB) (90), Enzyme Immunoassay (EIA) (71), ELISA (41), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (23), Immunhistochemie (IHC) (16), Durchflusszytometrie (FACS) (15), Funktionale Studien (Func) (14), Immunpräzipitation (IP) (13), Immunfluoreszenz (IF) (11), ELISA (Fangantikörper) (10), Neutralisierung (Neut) (10), ELISA (Detektionsantikörper) (9), Immunhistochemie (Paraffinschnitte) (IHC (p)) (7), Intrazelluläre Durchflusszytometrie (ICFC) (7), Dot Blot (Dot) (6), Radioimmunoassay (RIA) (4), ELISPOT (Detektionsantikörper) (3), ELISPOT (Fangantikörper) (2), Blockierende Antikörper (Inhibition) (1), Immunzytochemie (ICC) (1), Intrazellulärfärbung (IS) (1)
|
|
Konjugate
|
Biotin (21), FITC (11), Alexa Fluor 647 (2), HRP (1)
|
|
Epitope
|
Cleaved-Asp210 (2), C-Term (1)
|