IL-1 R1 Antikörper (RPE)

Antigen: IL-1 R1

Klonalität: Monoklonal (JAMA-147)

Wirt: Armenischer Hamster

Reaktivität: Maus

Konjugat: RPE

Produktnummer: ABIN488767

Produktbeschreibung

Isotyp: IgG

Klon: JAMA-147

Beschreibung: IL-1 binds two receptors, IL-1RI and IL-1RII. The ligands IL-1a and IL-1 exert all of their various biological actions by binding IL-1RI. IL-1RII has a shortened cytoplasmic domain that is unable to transduce signals and therefore acts as a decoy receptor and competitively antagonizes the binding of IL-1a and IL-1, thereby reducing their biological effects. Binding of the ligands to IL-1RI is enhanced by an accessory protein, IL-1R-AcP. IL-1RI is expressed on T cells, thymocytes, dendritic cells, fibroblasts, vascular endothelial cells, epithelial cells and neural cells. It is an 80 kD transmembrane glycoprotein.

Spezifität: Armenian Hamster Anti-Mouse IL-1 R1 (Clone JAMA-147) recognizes Mouse IL-1 R1. This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.

Anwendungen

Konzentration: 0.1 mg/ml

Buffer: This R-phycoerythrin (R-PE) conjugate is formulated in 0.01 M phosphate buffered saline (PBS) pH 7.4, 150 mM NaCl, 1% BSA and 0.09% sodium azide as a preservative. Storage and Stability. Endotoxin: Functional.

Lagerung: This R-PE conjugate is stable when stored at 2-8°C. Do not freeze.

Beschränkungen: Nur für Forschungszwecke einsetzbar