WNK1 Antikörper (Middle Region)

Produktnummer ABIN4886765

Produktdetails anti-WNK1 Antikörper

Target: WNK1 (WNK Lysine Deficient Protein Kinase 1 (WNK1))

Bindungsspezifität: AA 1154-1195, Middle Region

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser WNK1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Verwendungszweck: Rabbit IgG polyclonal antibody for Serine/threonine-protein kinase WNK1(WNK1) detection. Tested with WB, IHC-P in Human,Mouse,Rat.

Sequenz: DNPEEIATIM VNNDFILAIE RESFVDQVRE IIEKADEMLS ED

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Produktmerkmale: Rabbit IgG polyclonal antibody for Serine/threonine-protein kinase WNK1(WNK1) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Gene Name: WNK lysine deficient protein kinase 1
Protein Name: Serine/threonine-protein kinase WNK1

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence in the middle region of human WNK1 (1154-1195aa DNPEEIATIMVNNDFILAIERESFVDQVREIIEKADEMLSED), different from the related mouse and rat sequences by one amino acid.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Rat, Predicted Species: Human
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Details zu WNK1

Target: WNK1 (WNK Lysine Deficient Protein Kinase 1 (WNK1))

Andere Bezeichnung: WNK1 (WNK1 Produkte)

Synonyme: HSAN2 antikoerper, HSN2 antikoerper, KDP antikoerper, PRKWNK1 antikoerper, PSK antikoerper, p65 antikoerper, WNK1 antikoerper, kdp antikoerper, psk antikoerper, hsn2 antikoerper, hsan2 antikoerper, pha2c antikoerper, prkwnk1 antikoerper, 6430573H23Rik antikoerper, EG406236 antikoerper, Hsn2 antikoerper, Prkwnk1 antikoerper, mKIAA0344 antikoerper, ATWNK1 antikoerper, T9J14.14 antikoerper, T9J14_14 antikoerper, ZIK4 antikoerper, with no lysine (K) kinase 1 antikoerper, WNK lysine deficient protein kinase 1 antikoerper, WNK lysine deficient protein kinase 1 L homeolog antikoerper, serine/threonine-protein kinase WNK1 antikoerper, with no lysine (K) kinase 1 antikoerper, WNK1 antikoerper, wnk1.L antikoerper, wnk1 antikoerper, LOC100056745 antikoerper, Wnk1 antikoerper

Hintergrund: WNK lysine deficient protein kinase 1, also known as WNK1, is an enzyme that in humans is encoded by the WNK1 gene. The human gene is located on short arm of chromosome 12 (12p13.3). This gene encodes a member of the WNK subfamily of serine/threonine protein kinases. The encoded protein may be a key regulator of blood pressure by controlling the transport of sodium and chloride ions. Mutations in this gene have been associated with pseudohypoaldosteronism type II and hereditary sensory neuropathy type II. Alternatively spliced transcript variants encoding different isoforms have been described but the full-length nature of all of them has yet to be determined.

Synonyms: HSAN2 | HSN2 | KDP | Kinase deficient protein | p65 | PRKWNK1 | PSK | WNK1 | WNK 1 | Q9H4A3

Gen-ID: 65125

UniProt: Q9H4A3