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Fibrinogen beta Chain Antikörper (Middle Region)

FGB Reaktivität: Human, Ratte, Maus WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN4886579
  • Target Alle Fibrinogen beta Chain (FGB) Antikörper anzeigen
    Fibrinogen beta Chain (FGB)
    Bindungsspezifität
    • 9
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 193-225, Middle Region
    Reaktivität
    • 56
    • 16
    • 11
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Ratte, Maus
    Wirt
    • 55
    • 14
    • 1
    Kaninchen
    Klonalität
    • 56
    • 14
    Polyklonal
    Konjugat
    • 37
    • 12
    • 7
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser Fibrinogen beta Chain Antikörper ist unkonjugiert
    Applikation
    • 50
    • 26
    • 23
    • 12
    • 9
    • 7
    • 6
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Verwendungszweck
    Rabbit IgG polyclonal antibody for Fibrinogen beta chain (FGB) detection. Tested with WB in Human,Mouse,Rat.
    Sequenz
    TNLRVLRSIL ENLRSKIQKL ESDVSAQMEY CRT
    Kreuzreaktivität (Details)
    No cross reactivity with other proteins.
    Produktmerkmale
    Rabbit IgG polyclonal antibody for Fibrinogen beta chain (FGB) detection. Tested with WB in Human,Mouse,Rat.
    Gene Name: fibrinogen beta chain
    Protein Name: Fibrinogen beta chain
    Aufreinigung
    Immunogen affinity purified.
    Immunogen
    A synthetic peptide corresponding to a sequence in the middle region of human FGB (193-225aa TNLRVLRSILENLRSKIQKLESDVSAQMEYCRT), different from the related mouse sequence by three amino acids, and from the related rat sequence by five amino acids.
    Isotyp
    IgG
    Top Product
    Discover our top product FGB Primärantikörper
  • Applikationshinweise
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat
    Notes: Tested Species: Species with positive results.
    Other applications have not been tested. Optimal dilutions should be determined by end users.
    Kommentare

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    Konzentration
    500 μg/mL
    Buffer
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
  • Target
    Fibrinogen beta Chain (FGB)
    Andere Bezeichnung
    FGB (FGB Produkte)
    Synonyme
    FGB antikoerper, 2510049G14Rik antikoerper, DKFZp470D0312 antikoerper, LOC100223598 antikoerper, fibrinogen antikoerper, Ab1-216 antikoerper, Ac1-581 antikoerper, wu:fa55c11 antikoerper, zgc:77116 antikoerper, fgb antikoerper, fibrinogen beta chain antikoerper, fibrinogen beta chain L homeolog antikoerper, FGB antikoerper, Fgb antikoerper, fgb antikoerper, fgb.L antikoerper
    Hintergrund
    Fibrinogen beta chain, mapped to 4q31.3, is also known as FGB. The protein encoded by this gene is the beta component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including afibrinogenemia, dysfibrinogenemia, hypodysfibrinogenemia and thrombotic tendency. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

    Synonyms: FGB | Fibrinogen beta chain | Fibrinopeptide B | HEL S 78p | HEL-S-78p | P02675
    Gen-ID
    2244
    UniProt
    P02675
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