Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

APOB Antikörper (AA 246-450)

APOB Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN4886467
  • Target Alle APOB Antikörper anzeigen
    APOB (Apolipoprotein B (APOB))
    Bindungsspezifität
    • 6
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 246-450
    Reaktivität
    • 92
    • 25
    • 22
    • 6
    • 3
    Human
    Wirt
    • 62
    • 35
    • 15
    • 2
    • 1
    Kaninchen
    Klonalität
    • 77
    • 36
    Polyklonal
    Konjugat
    • 48
    • 21
    • 17
    • 7
    • 5
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser APOB Antikörper ist unkonjugiert
    Applikation
    • 65
    • 46
    • 33
    • 17
    • 16
    • 15
    • 10
    • 8
    • 7
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Verwendungszweck
    Rabbit IgG polyclonal antibody for Apolipoprotein B-100(APOB) detection. Tested with WB, IHC-P in Human.
    Kreuzreaktivität (Details)
    No cross reactivity with other proteins.
    Produktmerkmale
    Rabbit IgG polyclonal antibody for Apolipoprotein B-100(APOB) detection. Tested with WB, IHC-P in Human.
    Gene Name: apolipoprotein B
    Protein Name: Apolipoprotein B-100
    Aufreinigung
    Immunogen affinity purified.
    Immunogen
    E. coli-derived human Apolipoprotein B recombinant protein (Position: Q246-N450). Human Apolipoprotein B shares 82.4% and 80.5% amino acid (aa) sequence identity with mouse and rat Apolipoprotein B, respectively.
    Isotyp
    IgG
    Top Product
    Discover our top product APOB Primärantikörper
  • Applikationshinweise
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
    IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
    Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.
    Kommentare

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    Konzentration
    500 μg/mL
    Buffer
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
  • Target
    APOB (Apolipoprotein B (APOB))
    Andere Bezeichnung
    APOB (APOB Produkte)
    Synonyme
    FLDB antikoerper, LDLCQ4 antikoerper, Ac1-060 antikoerper, Apo B-100 antikoerper, ApoB-100 antikoerper, ApoB-48 antikoerper, AI315052 antikoerper, apob-100 antikoerper, apob-48 antikoerper, APOB-100 antikoerper, ApoB(100) antikoerper, APOB antikoerper, apolipoprotein B antikoerper, APOB antikoerper, Apob antikoerper
    Hintergrund
    Apolipoprotein B (ApoB) is a protein that in humans is encoded by the APOB gene. This gene product is the main apolipoprotein of chylomicrons and low density lipoproteins. It occurs in plasma as two main isoforms, apoB-48 and apoB-100: the former is synthesized exclusively in the gut and the latter in the liver. The intestinal and the hepatic forms of apoB are encoded by a single gene from a single, very long mRNA. The two isoforms share a common N-terminal sequence. The shorter apoB-48 protein is produced after RNA editing of the apoB-100 transcript at residue 2180 (CAA->UAA), resulting in the creation of a stop codon, and early translation termination. Mutations in this gene or its regulatory region cause hypobetalipoproteinemia, normotriglyceridemic hypobetalipoproteinemia, and hypercholesterolemia due to ligand-defective apoB, diseases affecting plasma cholesterol and apoB levels.

    Synonyms: Apo B-100 | ApoB 100 | Apo B-48 | ApoB 48 | APOB | Apolipoprotein B 100 | Apolipoprotein B | Apolipoprotein B-48 | Apolipoprotein B48 | FLDB | LDLCQ4 | P04114
    Gen-ID
    338
    UniProt
    P04114
    Pathways
    Lipid Metabolism
Sie sind hier:
Kundenservice