ABCE1 Antikörper (AA 419-599)

Produktnummer ABIN4886410

Produktdetails anti-ABCE1 Antikörper

Target: ABCE1 (ATP-Binding Cassette, Sub-Family E (OABP), Member 1 (ABCE1))

Bindungsspezifität: AA 419-599

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ABCE1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Verwendungszweck: Rabbit IgG polyclonal antibody for ATP-binding cassette sub-family E member 1(ABCE1) detection. Tested with WB in Human,Mouse,Rat.

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Produktmerkmale: Rabbit IgG polyclonal antibody for ATP-binding cassette sub-family E member 1(ABCE1) detection. Tested with WB in Human,Mouse,Rat.
Gene Name: ATP binding cassette subfamily E member 1
Protein Name: ATP-binding cassette sub-family E member 1

Aufreinigung: Immunogen affinity purified.

Immunogen: E. coli-derived human ABCE1 recombinant protein (Position: K419-D599). Human ABCE1 shares 100% amino acid (aa) sequence identity with mouse ABCE1.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat
Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Details zu ABCE1

Target: ABCE1 (ATP-Binding Cassette, Sub-Family E (OABP), Member 1 (ABCE1))

Andere Bezeichnung: ABCE1 (ABCE1 Produkte)

Synonyme: ABCE1 antikoerper, DDBDRAFT_0188931 antikoerper, DDBDRAFT_0191227 antikoerper, DDB_0188931 antikoerper, DDB_0191227 antikoerper, abce1 antikoerper, MGC69546 antikoerper, DKFZp469K1416 antikoerper, ABC38 antikoerper, OABP antikoerper, RLI antikoerper, RNASEL1 antikoerper, RNASELI antikoerper, RNS4I antikoerper, C79080 antikoerper, Oabp antikoerper, RNS41 antikoerper, Rnaseli antikoerper, wu:fb34c09 antikoerper, wu:fe47b01 antikoerper, wu:fi09g07 antikoerper, zgc:111906 antikoerper, zgc:56045 antikoerper, Rns4i antikoerper, ATP binding cassette subfamily E member 1 antikoerper, 4Fe-4S ferredoxin, iron-sulfur binding domain-containing protein antikoerper, ATP-binding cassette sub-family E member 1 antikoerper, RNAse L inhibitor antikoerper, RNase L inhibitor antikoerper, ribosome biogenesis/translation initiation ATPase RLI antikoerper, ATP-binding cassette, sub-family E (OABP), member 1 antikoerper, ATP binding cassette subfamily E member 1 S homeolog antikoerper, ABCE1 antikoerper, abcE1 antikoerper, LOC100184673 antikoerper, LOC100213121 antikoerper, abce1 antikoerper, TP04_0855 antikoerper, PVX_115370 antikoerper, TERMP_RS03360 antikoerper, Abce1 antikoerper, abce1.S antikoerper

Hintergrund: ATP binding cassette E1 (ABCE1, also RNase L inhibitor) is an ATPase found in humans involved in viral assembly. It is a member of the ATP-binding cassette (ABC) transporters superfamily and OABP subfamily. ABCE1 inhibits the action of ribonuclease L. Ribonuclease L normally binds to 2-5A (5'-phosphorylated 2',5'-linked oligoadenylates) and inhibits the interferon-regulated 2-5A/RNase L pathway, which is used by viruses. ABCE1 heterodimerize with ribonuclease L and prevents its interaction with 2-5A, antagonizing the anti-viral properties of ribonuclease L, and allow the virus to synthesize viral proteins. It has also been implicated to have an effect in tumorcell proliferation and antiapoptosis.

Synonyms: ABC 38 | ABC38 | ABCE 1 | ABCE1 | HuHP 68 | HuHP68 | OABP | Ribonuclease 4 inhibitor | Ribonuclease L inhibitor | RLI | RNase L inhibitor | RNASEL1 | RNASELI | RNS 4I | RNS4I | P61221

Gen-ID: 6059

UniProt: P61221