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Angiotensin-converting enzyme Antikörper

Antigen

Angiotensin-converting enzyme

Klonalität Monoklonal (4F3-E6-H6)
Wirt

Maus

Reaktivität

Human

Applikation
ELISA, Western Blot (WB)
Produktnummer ABIN488256
Menge 100µg  (1. 000mg/ml)
Preis 382,42 €   Zzgl. Versandkosten €20,00 und MWSt
Lieferung nach
Verfügbarkeit Lieferung in 5 bis 7 Werktagen

Produktbeschreibung

Gen-ID ACE1
Swiss-Prot P12821
Immunogen Recombinant fragment, corresponding to amino acids 198-481aa of human ACE1(N-terminus).
Format Purified
Isotyp IgG1  (Passende Sekundärantikörper)
Klon 4F3-E6-H6
Beschreibung This gene encodes an enzyme involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. Many studies have associated the presence or absence of a 287 bp Alu repeat element in this gene with the levels of circulating enzyme or cardiovascular pathophysiologies. Two most abundant alternatively spliced variants of this gene encode two isozymes - the somatic form and the testicular form that are equally active. Multiple additional alternatively spliced variants have been identified but their full length nature has not been determined. Caution hazardous ingredient: Sodium azide, avoid exposure to skin and eyes, ingestion, and contact with heat, acids, and metals or metal ions. Wash exposed skin with soap and water. Flush eyes with water. Do not discard into plumbing.
Spezifität Mouse monoclonal to ACE1

Anwendungen

Applikationshinweise ELISA: 1/5000 – 1/20000. WB: 1/100-1/2000
Konzentration 1. 000mg/ml
Reinheit > 90%
Reinigung Protein G-Sepharose affinity purified
Buffer Preservative: 0. 02% Sodium Azide and 50% glycerol, 1% BSA, PBS, PH7. 4.
Lagerung Store at -20°C. Avoid repeated freeze / thaw cycles. Ship at 4°-10°
Forschungsgebiet Krebs, Signaltransduktion, Kardiovaskuläres System, Zellstruktur, Proteolyse / Ubiquitin, Metalloprotease, Inflammation, Stammzellen, Hämopoetische Vorläufer, Zell-/Gewebemarker, Blutbestandteile
Beschränkungen Nur für Forschungszwecke einsetzbar