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beta-Catenin (CTNNB1) Antikörper

Antigen

beta-Catenin (CTNNB1)

Synonyme
CTNNB, FLJ25606, FLJ37923, DKFZp686D02253, Mesc, Catnb, ctnnb, id:ibd2058, wu:fb73e10, wu:fi81c06, wu:fk25h01, ARM, Beta-cat, Beta-catenin, EG:86E4.6, beta-cat-arm, l(1)2Bv, l(1)G0192, l(1)G0234, l(1) ... mehr anzeigen
Klonalität Monoklonal (3B12-A12-E3)
Wirt
Reaktivität
Alternativen

Human

Applikation
Alternativen ELISA, Western Blot (WB)
Produktnummer ABIN488242
Menge 100µg  (1. 000mg/ml)
Preis 382,42 €   Zzgl. Versandkosten €20,00 und MWSt
Lieferung nach
Verfügbarkeit Lieferung in 5 bis 7 Werktagen

Produktbeschreibung

Weitere Bezeichnung Catenin beta-1
Gen-ID CTNNB1
Swiss-Prot P35222
Immunogen A synthetic peptide (CGGGAPSLSGKGNPEEEDVDTS) of human CTNNB1 (N-terminus).
Format Purified
Isotyp IgG1  (Passende Sekundärantikörper)
Klon 3B12-A12-E3
Beschreibung The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Three transcript variants encoding the same protein have been found for this gene. Caution hazardous ingredient: Sodium azide, avoid exposure to skin and eyes, ingestion, and contact with heat, acids, and metals or metal ions. Wash exposed skin with soap and water. Flush eyes with water. Do not discard into plumbing.
Spezifität Mouse monoclonal to CTNNB1
Synonyme CTNNB, FLJ25606, FLJ37923, DKFZp686D02253, Mesc, Catnb, ctnnb, id:ibd2058, wu:fb73e10, wu:fi81c06, wu:fk25h01, ARM, Beta-cat, Beta-catenin, EG:86E4.6, beta-cat-arm, l(1)2Bv, l(1)G0192, l(1)G0234, l(1)G0410, l(1)arm, t12687 ALR Dm, DmelCG11579, CG11579, beta-catenin, ctnnb1, MGC79992, MGC132060, Cibeta-catenin, CTNNB1, MGC52601, LOC576711, Ctnnb1, MGC139922

Anwendungen

Applikationshinweise ELISA: 1/5000 – 1/20000. WB: 1/100-1/2000
Konzentration 1. 000mg/ml
Reinheit > 90%
Reinigung Protein G-Sepharose affinity purified
Buffer Preservative: 0. 02% Sodium Azide and 50% glycerol, 1% BSA, PBS, PH7. 4.
Lagerung Store at -20°C. Avoid repeated freeze / thaw cycles. Ship at 4°-10°
Forschungsgebiet Kardiovaskuläres System, Artherosklerose, Inflammation, Krebs, Bakterien, Extrazelluläre Matrix, Zellstruktur, Stammzellen, Signaltransduktion, Neurogenese, Zytoskelett, Mikrofilamente
Beschränkungen Nur für Forschungszwecke einsetzbar

Alternativen

Alternativen zu Antigen "beta-Catenin (CTNNB1)", Typ "Antikörper" finden
Wirte Kaninchen (187), Maus (61)
Reaktivitäten Human (230), Maus (155), Ratte (Rattus) (138), Huhn (29), Hund (13), Rind (Kuh) (8), Schwein (6), Xenopus laevis (5), Hamster (2), Affe (1), Kaninchen (1), Schaf (1)
Applikationen Western Blot (WB) (219), Immunfluoreszenz (IF) (72), Immunpräzipitation (IP) (63), Enzyme Immunoassay (EIA) (52), Immunhistochemie (Paraffinschnitte) (IHC (p)) (50), Immunhistochemie (IHC) (40), ELISA (29), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (20), Durchflusszytometrie (FACS) (19), Dot Blot (Dot) (8), Immunzytochemie (ICC) (5), Immunhistochemie (formalinfixierte Schnitte) (IHC (f)) (2), Elektromobilitäts-Experimente (EMSA) (1), Immunoelectron Microscopy (IEM) (1)
Konjugate Biotin (5), Cy3 (2), FITC (2), HRP (2), Alexa Flour 488 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), Gold (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy7 (1), RBITC (1)
Epitope pSer33 (10), pSer37 (10), Ab-33 (5), Ab-37 (5), Ab-41/45 (5), C-Term (5), pSer33/37 (5), pThr41/Ser45 (5), pThr41/pSer45 (5), Ab-654 (3), pTyr654 (3), pTyr86 (3), exon 3 (2), pSer45 (2), Ab-489 (1), Core (1), dep27-37 (1), dep35-50 (1), pTyr489 (1)