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CDK6 Antikörper

CDK6 Reaktivität: Human, Maus, Ratte WB, IP Wirt: Maus Monoclonal DCS-83 unconjugated
Produktnummer ABIN488121
  • Target Alle CDK6 Antikörper anzeigen
    CDK6 (Cyclin-Dependent Kinase 6 (CDK6))
    Reaktivität
    • 126
    • 47
    • 24
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    Human, Maus, Ratte
    Wirt
    • 110
    • 16
    Maus
    Klonalität
    • 99
    • 27
    Monoklonal
    Konjugat
    • 67
    • 7
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser CDK6 Antikörper ist unkonjugiert
    Applikation
    • 75
    • 38
    • 29
    • 27
    • 27
    • 24
    • 23
    • 12
    • 8
    • 5
    • 2
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunoprecipitation (IP)
    Spezifität
    This antibody reacts with Cdk6.
    Kreuzreaktivität (Details)
    Species reactivity (tested):Human, Mouse and Rat.
    Aufreinigung
    Protein-A Sepharose Chromatography.
    Immunogen
    Recombinant Cdk6 protein. Remarks: Hybridoma was established by fusion of mouse myeloma cell NS-2 with Balb/c mouse splenocyte.
    Klon
    DCS-83
    Isotyp
    IgG1
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  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1.0 mg/mL
    Buffer
    PBS, pH 7.2 containing 50 % Glycerol without preservatives.
    Konservierungsmittel
    Without preservative
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store the antibody prior to reconstitution at -20 °C. Following reconstitution the antibody can be stored at 2-8 °C for one month or at -20 °C for longer.
  • Target
    CDK6 (Cyclin-Dependent Kinase 6 (CDK6))
    Andere Bezeichnung
    CDK6 (CDK6 Produkte)
    Synonyme
    CDK6 antikoerper, PLSTIRE antikoerper, 5830411I20 antikoerper, AI504062 antikoerper, Crk2 antikoerper, cyclin dependent kinase 6 antikoerper, cyclin-dependent kinase 6 antikoerper, CDK6 antikoerper, Cdk6 antikoerper
    Hintergrund
    Cdk6 (Cyclin-dependent kinase-6) is a 38-40 kDa member of the Cdk family of mitotic kinases involved in cell cycle progression. The Cdk6 phosphoprotein, like Cdk4, associates with D-cyclins to regulate cell proliferation. Following translocation to the nucleus, the Cdk6 is phosphorylated by CAK, and the Cdk6 complex, in association with PCNA, phosphorylates the retinoblastoma (Rb) protein. Overexpression of Cdk6 has been associated with several different types of cancer.Synonyms: Cell division protein kinase 6, PLSTIRE, Serine/threonine-protein kinase PLSTIRE
    Gen-ID
    1021
    NCBI Accession
    NP_001250
    UniProt
    Q00534
    Pathways
    Zellzyklus, Mitotic G1-G1/S Phases
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