CDK6 Antikörper
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- Target Alle CDK6 Antikörper anzeigen
- CDK6 (Cyclin-Dependent Kinase 6 (CDK6))
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser CDK6 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunoprecipitation (IP)
- Spezifität
- This antibody reacts with Cdk6.
- Kreuzreaktivität (Details)
- Species reactivity (tested):Human, Mouse and Rat.
- Aufreinigung
- Protein-A Sepharose Chromatography.
- Immunogen
- Recombinant Cdk6 protein. Remarks: Hybridoma was established by fusion of mouse myeloma cell NS-2 with Balb/c mouse splenocyte.
- Klon
- DCS-83
- Isotyp
- IgG1
- Top Product
- Discover our top product CDK6 Primärantikörper
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1.0 mg/mL
- Buffer
- PBS, pH 7.2 containing 50 % Glycerol without preservatives.
- Konservierungsmittel
- Without preservative
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- Store the antibody prior to reconstitution at -20 °C. Following reconstitution the antibody can be stored at 2-8 °C for one month or at -20 °C for longer.
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- Target
- CDK6 (Cyclin-Dependent Kinase 6 (CDK6))
- Andere Bezeichnung
- CDK6 (CDK6 Produkte)
- Synonyme
- CDK6 antikoerper, PLSTIRE antikoerper, 5830411I20 antikoerper, AI504062 antikoerper, Crk2 antikoerper, cyclin dependent kinase 6 antikoerper, cyclin-dependent kinase 6 antikoerper, CDK6 antikoerper, Cdk6 antikoerper
- Hintergrund
- Cdk6 (Cyclin-dependent kinase-6) is a 38-40 kDa member of the Cdk family of mitotic kinases involved in cell cycle progression. The Cdk6 phosphoprotein, like Cdk4, associates with D-cyclins to regulate cell proliferation. Following translocation to the nucleus, the Cdk6 is phosphorylated by CAK, and the Cdk6 complex, in association with PCNA, phosphorylates the retinoblastoma (Rb) protein. Overexpression of Cdk6 has been associated with several different types of cancer.Synonyms: Cell division protein kinase 6, PLSTIRE, Serine/threonine-protein kinase PLSTIRE
- Gen-ID
- 1021
- NCBI Accession
- NP_001250
- UniProt
- Q00534
- Pathways
- Zellzyklus, Mitotic G1-G1/S Phases
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