TGFBI Antikörper (Internal Region)

Produktnummer ABIN488042

Produktdetails anti-TGFBI Antikörper

Target: TGFBI (Transforming Growth Factor, beta-Induced, 68kDa (TGFBI))

Bindungsspezifität: Internal Region

Reaktivität: Human, Maus, Ratte, Hund

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser TGFBI Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Sequenz: c-QLYTDRTEKL RPE

Spezifität: Recognizes TGFBI/BIGH3.

Kreuzreaktivität (Details): Species reactivity (expected):Mouse, Rat and Canine (Dog).
Species reactivity (tested):Human.

Aufreinigung: Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide.

Immunogen: Peptide with sequence from the Internal region of the protein sequence according to NP_000349.1. Genename: TGFBI

Anwendungsinformationen

Applikationshinweise: Peptide ELISA: Detection Limit Dilution: 1/32000. Western Blot: 0.2-0.5 μg/mL. Approx 70 kDa band observed in Human, Mouse and RatKidney lysates (calculated MW of 74.0 kDa according to Human NP_000349.1).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Details zu TGFBI

Target: TGFBI (Transforming Growth Factor, beta-Induced, 68kDa (TGFBI))

Andere Bezeichnung: TGFBI / BIGH3 (TGFBI Produkte)

Synonyme: TGFBI antikoerper, BIGH3 antikoerper, CDB1 antikoerper, CDG2 antikoerper, CDGG1 antikoerper, CSD antikoerper, CSD1 antikoerper, CSD2 antikoerper, CSD3 antikoerper, EBMD antikoerper, LCD1 antikoerper, 68kDa antikoerper, AI181842 antikoerper, AI747162 antikoerper, Beta-ig antikoerper, big-h3 antikoerper, Big-h3 antikoerper, MP70 antikoerper, MP78 antikoerper, hm:zeh0933 antikoerper, wu:fa13f05 antikoerper, zgc:110495 antikoerper, transforming growth factor beta induced antikoerper, transforming growth factor, beta induced antikoerper, transforming growth factor, beta-induced antikoerper, TGFBI antikoerper, Tgfbi antikoerper, tgfbi antikoerper

Hintergrund: TGFBI, also known as BIGH3 and βig-h3, is an extracellular matrix protein induced by transforming growth factor (TGF)-beta 1. TGFBI protein is involved in cell growth, cell differentiation, wound healing and cell adhesion. In addition, some missense mutations of TGFBI were identified in families affected with human autosomal dominant corneal dystrophies. BIGH3 gene encodes for a 683 amino-acid protein containing an RGD motif and four internal repeated domains which have highly conserved sequences founded in several species (Fasciclin domain).Synonyms: Beta ig-h3, Kerato-epithelin, RGD-CAP, RGD-containing collagen-associated protein, Transforming growth factor-beta-induced protein ig-h3

Gen-ID: 7045

NCBI Accession: NP_000349

UniProt: Q15582