DIXDC1 Antikörper (Internal Region)

Produktnummer ABIN487984

Produktdetails anti-DIXDC1 Antikörper

Target: DIXDC1 (DIX Domain Containing 1 (DIXDC1))

Bindungsspezifität: Internal Region

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser DIXDC1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Spezifität: This antibody reacts to CCAR1.

Kreuzreaktivität (Details): Species reactivity (expected):Canine, Bovine, Porcine.
Species reactivity (tested):Mouse, Rat.

Aufreinigung: Affinity chromatography

Immunogen: Peptide with sequence RYCKERPSKDKE, from the internal region (near C-Terminus) of the protein sequence according to NP_060707.2.

Anwendungsinformationen

Applikationshinweise: Peptide ELISA: 1/16000. Western blot: Approx 120 kDa band observed in Mouse and Rat Skeletal Muscle lysates(calculated MW of 130 kDa according to Mouse NP_080477.1 and Rat NP_001102005.1). Recommended concentration: 1 - 3 μg/mL. An additional band of unknown identity was also consistently observed at 30 kDa. Thisband was successfully blocked by incubation with the immunizing peptide.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Details zu DIXDC1

Target: DIXDC1 (DIX Domain Containing 1 (DIXDC1))

Andere Bezeichnung: Dixin (DIXDC1 Produkte)

Synonyme: CCD1 antikoerper, 4930563F16Rik antikoerper, BC048182 antikoerper, Ccd1 antikoerper, Ccd1Aalpha1L antikoerper, Ccd1Abeta1L antikoerper, Ccd1BalphaL antikoerper, Ccd1BbetaL antikoerper, Ccd1CL antikoerper, mKIAA1735 antikoerper, ccd1 antikoerper, dixdc1 antikoerper, im:7138279 antikoerper, DIX domain containing 1 antikoerper, DIX domain containing 1a antikoerper, DIX domain containing 1b antikoerper, DIXDC1 antikoerper, dixdc1 antikoerper, Dixdc1 antikoerper, dixdc1a antikoerper, dixdc1b antikoerper

Hintergrund: DIXDC1 belongs to the DIXDC1 family and contains 1 CH (calponin homology) domain and 1 DIX domain. The coiled coil domain mediates interaction with MAP3K4 and inhibition of AXIN1 mediated JNK activation through MAP3K4. The DIX domain mediates interaction with AXIN1 and inhibition of AXIN1 mediated JNK activation through MAP3K1. Probably also mediates interaction with DVL2.Synonyms: CCD1, Coiled-coil protein DIX1, DIX domain-containing protein 1, DIX1, DIXDC1, KIAA1735

Gen-ID: 85458

NCBI Accession: NP_001033043

UniProt: Q155Q3