Methamphetamine (M-Amp) Antikörper

Antigen: Methamphetamine (M-Amp)

Klonalität: Polyklonal

Wirt: Schaf

Applikation: Enzyme Immunoassay (EIA)

Produktnummer: ABIN487762

Produktbeschreibung

Produktmerkmale: Synonyms: METH

Weitere Bezeichnung: Methamphetamine (p-NH2)

Immunogen: Methamphetamine (p-NH2)-BSA

Isotyp: IgG  (Passende Sekundärantikörper)

Beschreibung: Methamphetamine (METH) is closely related chemically to amphetamine (AMPH). METH isa potent central nervous system stimulant with additional peripheral sympathomimeticeffects. METH and AMPH have been used clinically in the treatment of obesity, minimalbrain dysfunction, narcolepsy, depression and to counter fatigue. They are also subjectedto widespread abuse. METH is an indirect agonists. It causes the release of newlysynthesized norepinephrine and dopamine and it blocks the re uptake of thesetransmitters from the synapse. This can lead to an increase in the concentration ofcatecholamines in the synapse as well as an overall increase in catecholaminergic activityin the brain. The mechanism of METH induced neurotoxicity for all monoaminergic celltypes may lie primarily with the dopaminergic system in the striatum. It may also lie withthe interaction between METH induced release of dopamine and its ability to inhibitmonoamine oxidase.

Spezifität: This antibody reacts to Methamphetamine (p-NH2).

Anwendungen

Applikationshinweise: ELISA: 9μg/ml. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.

Konzentration: 8.94mg/ml (U.V. abs @ 280nm)

Reinigung: Ig Fraction

Buffer: 20mM Phosphate, 150mM Sodium Chloride, pH 7.2 containing 0.09%Sodium Azide as preservative

Lagerung: Store the antibody at -20°C. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

Beschränkungen: Nur für Forschungszwecke einsetzbar