P105 (NFKB) Antikörper

Antigen: P105 (NFKB)

Klonalität: Monoklonal (2B3)

Wirt: Maus

Reaktivität: Human

Applikation: Immunhistochemie (Gefrierschnitte) (IHC (fro)), Immunhistochemie (Paraffinschnitte) (IHC (p)), Western Blot (WB)

Produktnummer: ABIN487358

Produktbeschreibung

Produktmerkmale: Synonyms: PANA, Proliferation Associated Nuclear Antigen, Proliferation Marker

Weitere Bezeichnung: P105

Immunogen: Activated peripheral blood nuclei

Kreuzreaktivität: Human

Isotyp: IgM  (Passende Sekundärantikörper)

Klon: 2B3

Beschreibung: The p105 protein found in all human cells in a dimeric form (105 kD) and monomeric form(41 kD), is a proliferation-associated nuclear antigen that is absent in non-cycling cells inthe Go phase. This protein is important in the synthesis and transport of RNA in the cellregulation cycle. During G2 , and mitosis, this protein is increased possibly due to theunmasking of nucleolar antigens.

Spezifität: The antibody recognizes human p105 protein. Other species not tested. Cellular localization: Nuclear.

Anwendungen

Applikationshinweise: Western Blot (1: 100 - 1: 200). Immunohistochemistry on frozen and Paraffin sections (1: 50 - 1: 100). Please note: Formalin-fixed paraffin-embedded (FFPE) tissue sections require pepsin ortrypsin digestion. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.

Reinigung: Supernatant

Buffer: PBS, pH 7.2, containing 0.02% BSA and 0.09% sodium azide

Lagerung: Keep as concentrated solution, aliquot and store at 4°C. Do not freeze. Shelf life: one year from despatch.

Forschungsgebiet: Transkriptionsfaktoren

Beschränkungen: Nur für Forschungszwecke einsetzbar