Maus anti-Human Ig (Light Chain), (Chain kappa) Antikörper

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Antigen
Epitop
Light Chain, Chain kappa
537
390
289
66
25
16
13
10
7
6
5
3
2
2
1
Reaktivität
Human
678
213
74
30
19
15
10
6
5
5
4
4
3
2
1
1
1
1
1
1
1
1
1
1
Wirt
Maus
399
391
158
78
21
7
4
1
1
Klonalität (Klon)
Monoklonal ()
Applikation
Enzyme Immunoassay (EIA), Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Optionen
Hersteller
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Hersteller Produkt- Nr.
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Klon A8B5
Isotyp IgG1
Keine Kreuzreaktivität Hamster, Schaf, Ziege, Kaninchen, Meerschweinchen
Kreuzreaktivität (Details) Species reactivity (tested):Human.
Reinigung Protein A affinity chromatography
Andere Bezeichnung Immunoglobulin
Hintergrund Immunoglobulin classes share the same basic four polypeptide chain structure of two heavy chains (five heavy chains types) and two light chains (kappa, lambda, both having a molecular weight of 22.5 kDa). Kappa and lambda consist of a variable region and a constant region and can easily be differentiated by the antigenic properties of the constant region. The ratio of kappa to lambda is 70:30.
Forschungsgebiet Secondary Antibodies, Virology
Applikationshinweise Flow cytometry. Positive control: Daudi human cell lineImmunohistochemistry on frozen and paraffin sections. ELISA.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Beschränkungen Nur für Forschungszwecke einsetzbar
Konzentration 1.0 mg/mL
Buffer Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung 4 °C/-20 °C
Informationen zur Lagerung Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer. Avoid repeatedfreezing and thawing.
Shelf life: one year from despatch.
Haltbarkeit 12 months
Bilder des Herstellers
Flow Cytometry (FACS) image for Mouse anti-Human Ig (Light Chain), (Chain kappa) antibody (ABIN487319) Mouse anti-Human Ig (Light Chain), (Chain kappa) antibody
Allgemeine Veröffentlichungen Avilés-Salas, Chanona-Vilchis, Candelaria-Hernández, Peña-Torres, Cuéllar-Mendoza: "[Plasmoblastic lymphoma initially recognized as ovarian tumor]." in: Ginecología y obstetricia de México, Vol. 80, Issue 6, pp. 430-4, 2012 (PubMed).

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Scheeren, Diehl, Smit, Beaumont, Naspetti, Bende, Blom, Karube, Ohshima, van Noesel, Spits: "IL-21 is expressed in Hodgkin lymphoma and activates STAT5: evidence that activated STAT5 is required for Hodgkin lymphomagenesis." in: Blood, Vol. 111, Issue 9, pp. 4706-15, 2008 (PubMed).

Konig, Wennemuth, Soyer, Hoffmann, Happle, Krause: "Vulvar amyloidosis mimicking giant condylomata acuminata in a patient with multiple myeloma." in: European journal of dermatology : EJD, Vol. 9, Issue 1, pp. 29-31, 1999 (PubMed).

Diaz de Domingo, Lardo, Romero Artaza, Merelli, Carbia, Sánchez Avalos: "[Immunocytochemistry techniques for the diagnosis of hematologic neoplasms]." in: Medicina, Vol. 59, Issue 1, pp. 11-6, 1999 (PubMed).

Siddiqui, Brandriss: "The Saccharomyces cerevisiae PUT3 activator protein associates with proline-specific upstream activation sequences." in: Molecular and cellular biology, Vol. 9, Issue 11, pp. 4706-12, 1990 (PubMed).

Franklin: "Structure and function of immunoglobulins." in: Acta endocrinologica. Supplementum, Vol. 194, pp. 77-95, 1975 (PubMed).