SPINK1 Antikörper (N-Term)

Produktnummer ABIN487126

Produktdetails anti-SPINK1 Antikörper

Target: SPINK1 (serine Peptidase Inhibitor, Kazal Type 1 (SPINK1))

Bindungsspezifität: N-Term

Reaktivität: Human, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SPINK1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: KVTGIFLLSA LALLSLSGNT GADSLGREAK CYNELNGCTK IYDPVCGTDG

Homologie: Human: 100%, Rabbit: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against SPINK1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human SPINK1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 79 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-SPINK1 Antikörper (ABIN487126)

Tomlins, Rhodes, Yu, Varambally, Mehra, Perner, Demichelis, Helgeson, Laxman, Morris, Cao, Cao, Andrén, Fall, Johnson, Wei, Shah, Al-Ahmadie, Eastham, Eggener, Fine, Hotakainen, Stenman, Tsodikov et al.: "The role of SPINK1 in ETS rearrangement-negative prostate cancers. ..." in: Cancer cell, Vol. 13, Issue 6, pp. 519-28, (2008) (PubMed).

Details zu SPINK1

Target: SPINK1 (serine Peptidase Inhibitor, Kazal Type 1 (SPINK1))

Andere Bezeichnung: SPINK1 (SPINK1 Produkte)

Synonyme: PCTT antikoerper, PSTI antikoerper, Spink3 antikoerper, TATI antikoerper, TCP antikoerper, Psti antikoerper, SPINK1 antikoerper, p12 antikoerper, serine peptidase inhibitor, Kazal type 1 antikoerper, SPINK1 antikoerper, Spink1 antikoerper

Hintergrund: SPINK1 is a trypsin inhibitor, which is secreted from pancreatic acinar cells into pancreatic juice. It is thought to function in the prevention of trypsin-catalyzed premature activation of zymogens within the pancreas and the pancreatic duct. Mutations in this gene are associated with hereditary pancreatitis and tropical calcific pancreatitis.
Alias Symbols: PCTT, PSTI, Spink3, TATI, TCP
Protein Interaction Partner: NRSN1, TMPRSS15, CTRC, ELN,
Protein Size: 79

Molekulargewicht: 8 kDa

Gen-ID: 6690

NCBI Accession: NM_003122, NP_003113

UniProt: P00995