ZEB1 Antikörper (N-Term)

Produktnummer ABIN486932

Produktdetails anti-ZEB1 Antikörper

Target: ZEB1 (Zinc Finger E-Box Binding Homeobox 1 (ZEB1))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Kaninchen, Hund, Rind (Kuh), Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ZEB1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Sequenz: KDDECESDAE NEQNHDPNVE EFLQQQDTAV IFPEAPEEDQ RQGTPEASGH

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against ZEB1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human ZEB1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 1124 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-ZEB1 Antikörper (ABIN486932)

Lobert, Graichen, Morris: "Coordinated regulation of ?-tubulin isotypes and epithelial-to-mesenchymal transition protein ZEB1 in breast cancer cells." in: Biochemistry, Vol. 52, Issue 32, pp. 5482-90, (2013) (PubMed).

Details zu ZEB1

Target: ZEB1 (Zinc Finger E-Box Binding Homeobox 1 (ZEB1))

Andere Bezeichnung: ZEB1 (ZEB1 Produkte)

Synonyme: ZFH/[d]EF1 antikoerper, kheper antikoerper, zeb1 antikoerper, zfhx1 antikoerper, bzp antikoerper, zeb antikoerper, tcf8 antikoerper, areb6 antikoerper, nil2a antikoerper, zfhep antikoerper, nil-2a antikoerper, zfhx1a antikoerper, nil-2-a antikoerper, MGC97552 antikoerper, TCF8 antikoerper, AREB6 antikoerper, BZP antikoerper, DELTAEF1 antikoerper, FECD6 antikoerper, NIL2A antikoerper, PPCD3 antikoerper, ZFHEP antikoerper, ZFHX1A antikoerper, 3110032K11Rik antikoerper, MEB1 antikoerper, Nil2 antikoerper, TCF-8 antikoerper, Tcf18 antikoerper, Tcf8 antikoerper, Tw antikoerper, ZEB antikoerper, Zfhep antikoerper, Zfhx1a antikoerper, Zfx1a antikoerper, Zfx1ha antikoerper, [delta]EF1 antikoerper, deltaEF1 antikoerper, deltaef1 antikoerper, fecd6 antikoerper, zinc finger E-box binding homeobox 1b antikoerper, zinc finger E-box binding homeobox 1 antikoerper, zinc finger E-box binding homeobox 1 S homeolog antikoerper, zeb1b antikoerper, zeb1 antikoerper, ZEB1 antikoerper, Zeb1 antikoerper, zeb1.S antikoerper

Hintergrund: ZEB1 is a zinc finger transcription factor that represses T-lymphocyte-specific IL2 gene expression by binding to a negative regulatory domain 100 nucleotides 5-prime of the IL2 transcription start site.ZEB1 encodes a zinc finger transcription factor that represses T-lymphocyte-specific IL2 gene (MIM 147680) expression by binding to a negative regulatory domain 100 nucleotides 5-prime of the IL2 transcription start site (Williams et al., 1991 [PubMed 1840704]).[supplied by OMIM].
Alias Symbols: AREB6, BZP, MGC133261, NIL-2-A, NIL-2A, TCF8, ZEB, ZFHEP, ZFHX1A, FECD6, NIL2A, PPCD3, DELTAEF1
Protein Interaction Partner: SUMO1, CDK6, GTF2A1, UBR4, SUMO2, SIRT1, SOX2, CTBP2, CTBP1, SMAD7, SMAD6, SMARCA4, SERPINH1, SMAD3, EP300, DRAP1, KAT5, SMAD2, SMAD1, CDH1,
Protein Size: 1124

Molekulargewicht: 124 kDa

Gen-ID: 6935

NCBI Accession: NM_030751, NP_110378

UniProt: P37275

Pathways: Regulation of Muscle Cell Differentiation