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MTOR Antikörper (pSer2448)

mTOR Reaktivität: Human, Maus, Ratte WB, IHC, ELISA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN482522
  • Target Alle MTOR (mTOR) Antikörper anzeigen
    MTOR (mTOR) (Mechanistic Target of Rapamycin (serine/threonine Kinase) (mTOR))
    Bindungsspezifität
    • 34
    • 28
    • 23
    • 15
    • 12
    • 11
    • 9
    • 7
    • 5
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 2415-2464, pSer2448
    Reaktivität
    • 214
    • 140
    • 121
    • 23
    • 17
    • 12
    • 7
    • 6
    • 6
    • 5
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 194
    • 16
    • 2
    • 2
    Kaninchen
    Klonalität
    • 174
    • 39
    Polyklonal
    Konjugat
    • 110
    • 11
    • 10
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 6
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser MTOR Antikörper ist unkonjugiert
    Applikation
    • 148
    • 65
    • 63
    • 52
    • 52
    • 44
    • 36
    • 36
    • 17
    • 17
    • 12
    • 7
    • 3
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA
    Spezifität

    mTOR (Phospho-Ser2448) Antibody detects endogenous levels of mTOR only when phosphorylated at Ser2448.

    PhosphorylationH:S2448 M:S2448 R:S2448

    Aufreinigung
    The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.
    Reinheit
    > 95 %
    Immunogen
    The antiserum was produced against synthesized peptide derived from human mTOR around the phosphorylation site of Ser2448.
    Isotyp
    IgG
    Top Product
    Discover our top product mTOR Primärantikörper
  • Applikationshinweise
    WB: 1:500~1:1000 IHC: 1:50~1:100 ELISA: 1:40000
    Kommentare

    Unigene-Number: Hs.338207 (NCBI Gene Symbol: MTOR)

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Stable at -20°C for at least 1 year.
    Haltbarkeit
    12 months
  • Luo, Yoneda, Ohmori, Sasaki, Shimbo, Eto, Kato, Miyano, Kobayashi, Sasahira, Chihara, Kuniyasu: "Cancer usurps skeletal muscle as an energy repository." in: Cancer research, Vol. 74, Issue 1, pp. 330-40, (2014) (PubMed).

  • Target
    MTOR (mTOR) (Mechanistic Target of Rapamycin (serine/threonine Kinase) (mTOR))
    Andere Bezeichnung
    mTOR (mTOR Produkte)
    Synonyme
    FRAP1 antikoerper, FRAP antikoerper, FRAP2 antikoerper, RAFT1 antikoerper, RAPT1 antikoerper, 2610315D21Rik antikoerper, AI327068 antikoerper, Frap1 antikoerper, flat antikoerper, frap1 antikoerper, tor antikoerper, wu:fc22h08 antikoerper, mechanistic target of rapamycin kinase antikoerper, mechanistic target of rapamycin antikoerper, mechanistic target of rapamycin (serine/threonine kinase) antikoerper, MTOR antikoerper, Mtor antikoerper, mtor antikoerper
    Hintergrund

    Synonyms: FRAP, FRAP1, FRAP2, RAFT1, Rapamycin target protein, kinase mTOR

    NCBI Gene Symbol: MTOR

    Molekulargewicht
    288 kDa
    Gen-ID
    2475
    OMIM
    601231
    UniProt
    P42345
    Pathways
    PI3K-Akt Signalweg, RTK Signalweg, AMPK Signaling, Interferon-gamma Pathway, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Regulation of Actin Filament Polymerization, Regulation of Muscle Cell Differentiation, Regulation of Cell Size, Skeletal Muscle Fiber Development, Regulation of Carbohydrate Metabolic Process, Autophagie, CXCR4-mediated Signaling Events, BCR Signaling, Warburg Effekt
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