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PTPN11 Antikörper (pTyr542)

PTPN11 Reaktivität: Human, Maus, Ratte WB, IHC, ELISA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN481806
  • Target Alle PTPN11 Antikörper anzeigen
    PTPN11 (Protein tyrosine Phosphatase, Non-Receptor Type 11 (PTPN11))
    Bindungsspezifität
    • 34
    • 25
    • 15
    • 15
    • 9
    • 7
    • 7
    • 6
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 508-557, pTyr542
    Reaktivität
    • 161
    • 119
    • 109
    • 10
    • 10
    • 10
    • 10
    • 9
    • 8
    • 7
    • 5
    • 5
    • 4
    • 3
    • 2
    • 1
    Human, Maus, Ratte
    Wirt
    • 172
    • 18
    • 2
    • 1
    Kaninchen
    Klonalität
    • 152
    • 41
    Polyklonal
    Konjugat
    • 90
    • 12
    • 10
    • 9
    • 9
    • 9
    • 9
    • 9
    • 8
    • 5
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser PTPN11 Antikörper ist unkonjugiert
    Applikation
    • 128
    • 53
    • 44
    • 27
    • 26
    • 26
    • 25
    • 16
    • 16
    • 7
    • 6
    • 5
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA
    Spezifität

    SHP-2 (Phospho-Tyr542) Antibody detects endogenous levels of SHP-2 only when phosphorylated at Tyr542.

    PhosphorylationH:Y542 M:Y546 R:Y542

    Aufreinigung
    The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.
    Reinheit
    > 95 %
    Immunogen
    The antiserum was produced against synthesized peptide derived from human SHP-2 around the phosphorylation site of Tyr542.
    Isotyp
    IgG
    Top Product
    Discover our top product PTPN11 Primärantikörper
  • Applikationshinweise
    WB: 1:500~1:1000 IHC: 1:50~1:100 ELISA: 1:40000
    Kommentare

    Unigene-Number: Hs.506852, Hs.646231 (NCBI Gene Symbol: PTPN11)

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Stable at -20°C for at least 1 year.
    Haltbarkeit
    12 months
  • Target
    PTPN11 (Protein tyrosine Phosphatase, Non-Receptor Type 11 (PTPN11))
    Andere Bezeichnung
    SHP-2 (PTPN11 Produkte)
    Synonyme
    BPTP3 antikoerper, CFC antikoerper, NS1 antikoerper, PTP-1D antikoerper, PTP2C antikoerper, SH-PTP2 antikoerper, SH-PTP3 antikoerper, SHP2 antikoerper, 2700084A17Rik antikoerper, AW536184 antikoerper, PTP1D antikoerper, SAP-2 antikoerper, SHP-2 antikoerper, Shp2 antikoerper, Syp antikoerper, SYP antikoerper, bptp3 antikoerper, cfc antikoerper, ns1 antikoerper, ptp-2 antikoerper, ptp2c antikoerper, ptpn11 antikoerper, ptpn11-a antikoerper, ptpn11-b antikoerper, shp-2 antikoerper, shp2 antikoerper, fa14b09 antikoerper, wu:fa14b09 antikoerper, wu:fi24f03 antikoerper, zgc:55388 antikoerper, zgc:63553 antikoerper, protein tyrosine phosphatase, non-receptor type 11 antikoerper, protein tyrosine phosphatase, non-receptor type 11 S homeolog antikoerper, protein tyrosine phosphatase, non-receptor type 11, a antikoerper, protein tyrosine phosphatase, non-receptor type 11, b antikoerper, PTPN11 antikoerper, Ptpn11 antikoerper, ptpn11.S antikoerper, ptpn11a antikoerper, ptpn11b antikoerper
    Substanzklasse
    Viral Protein
    Hintergrund

    Synonyms: PTN11, PTP-1D, PTP-2C, PTP2C, PTPN11, Protein-tyrosine phosphatase 2C, Protein-tyrosine phosphatase, non-receptor type 11, SH-PTP2, SH-PTP3, SHPTP2

    NCBI Gene Symbol: PTPN11

    Molekulargewicht
    68 kDa
    Gen-ID
    5781
    OMIM
    151100
    UniProt
    Q06124
    Pathways
    JAK-STAT Signalweg, RTK Signalweg, T-Zell Rezeptor Signalweg, Interferon-gamma Pathway, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Negative Regulation of Hormone Secretion, Carbohydrate Homeostasis, Toll-Like Receptors Cascades, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, VEGFR1 Specific Signals, BCR Signaling, Warburg Effekt
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