ACE Antikörper

Antigen: ACE

Klonalität: Monoklonal

Wirt: Maus

Reaktivität: Human

Applikation: Western Blot (WB), ELISA, Immunhistochemie (Paraffinschnitte) (IHC (p))

Produktnummer: ABIN471163

Produktbeschreibung

Swiss-Prot: P12821

Immunogen: Purified protein, Denatured human kidney CD143 (Angiotensin converting enzyme).

Isotyp: IgG1  (Passende Sekundärantikörper)

Beschreibung: Gene: ACE, Standard Gene Symbol: ACE, Family: Protease, Subfamily: Metallopeptidase M2, Synonyms: ACE, ACE1, Angiotensin Converting Enzyme 1, ANGIOTENSIN I-CONVERTING ENZYME, Angiotensin-converting enzyme, CD143, DCP, DCP1, DIPEPTIDYL CARBOXYPEPTIDASE, DIPEPTIDYL CARBOXYPEPTIDASE 1, KININASE II, MGC26566, MVCD3, Peptidyl-dipeptidase A

Spezifität: Recognizes human CD143, also know as angiotensin-converting enzyme (ACE). CD143 exists in two forms, a 170kD somatic form and a 90kD germinal form. The somatic form is expressed by endothelial cells (especially those of lung capillaries and arterioles), epithelial cells (especially in proximal renal tubules and small intestine), by some neuronal cells and variably by some macrophages and T lymphocytes. The germinal form is expressed by spermatozoa. Study of CD143 may be relevant to fertility (especially sperm-egg interactions), atherosclerosis and in drug targeting to the lung. This clone recognizes denatured ACE, binding to an epitope in the C domain and has been reported to be active in Western blotting. Species cross-reactivity: Human, monkey, rabbit, bovine, canine, feline, guinea pig, rat, mouse. Predicted Reactivities: Cow (Bovine),Cat (Feline),Dog (Canine),Guinea Pig,Monkey,Mouse (Murine),Rabbit,Rat (Rattus).

Anwendungen

Applikationshinweise: ELISA, IHC-P, WB (1:50 - 1:100)

Reinigung: Supernatant

Buffer: Tissue Culture Supernatant. Supplied as a liquid, 0.1% sodium azide.

Lagerung: Long term: -20°C, Short term: +4°C

Beschränkungen: Nur für Forschungszwecke einsetzbar