SPHK1 Antikörper (pSer225)
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- Target Alle SPHK1 Antikörper anzeigen
- SPHK1 (Sphingosine Kinase 1 (SPHK1))
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Bindungsspezifität
- pSer225
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Reaktivität
- Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser SPHK1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Spezifität
- This antibody detects Sphingosine Kinase 1 (pSer225). Antibody shows some cross reactivity (~10 % by ELISA) with other phosphoserine containing proteins.
- Aufreinigung
- Affinity chromatography
- Immunogen
- A synthetic peptide incorporating the serine 225 phosphorylation site of mouse sphingosine kinase 1
- Isotyp
- IgG
- Top Product
- Discover our top product SPHK1 Primärantikörper
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anti-Sphingosine Kinase 1 (SPHK1) (AA 286-315) antibody
SPHK1 Reaktivität: Human, Maus, Ratte WB, IHC (p) Wirt: Kaninchen Polyclonal RB03621 unconjugated
anti-Sphingosine Kinase 1 (SPHK1) (AA 1-384) antibodySPHK1 Reaktivität: Human WB, ELISA Wirt: Maus Monoclonal 1D6 unconjugated
anti-Sphingosine Kinase 1 (SPHK1) (AA 1-30), (N-Term) antibodySPHK1 Reaktivität: Human WB Wirt: Kaninchen Polyclonal RB3619 unconjugated
anti-Sphingosine Kinase 1 (SPHK1) (AA 313-343) antibodySPHK1 Reaktivität: Human WB, IHC, ELISA, FACS Wirt: Kaninchen Polyclonal unconjugated
anti-Sphingosine Kinase 1 (SPHK1) (AA 286-315) antibodySPHK1 Reaktivität: Human, Maus, Ratte, Primate WB, IHC, ELISA Wirt: Kaninchen Polyclonal unconjugated
anti-Sphingosine Kinase 1 (SPHK1) (AA 148-398) antibodySPHK1 Reaktivität: Human WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Sphingosine Kinase 1 (SPHK1) (AA 1-384) antibodySPHK1 Reaktivität: Human WB, IHC, ELISA, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Sphingosine Kinase 1 (SPHK1) (AA 313-343), (C-Term) antibodySPHK1 Reaktivität: Human WB, IHC (p), FACS Wirt: Kaninchen Polyclonal RB15395 unconjugated
anti-Sphingosine Kinase 1 (SPHK1) (AA 59-89), (N-Term) antibodySPHK1 Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal RB15394 unconjugated
anti-Sphingosine Kinase 1 (SPHK1) (AA 50-384) antibodySPHK1 Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
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Western Blot: (1-5 μg/mL).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Buffer
- PBS, 0.08 % Sodium Azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store the product (in aliquots) at -20 °C. Can be shipped at 2 - 8 °C.
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- Target
- SPHK1 (Sphingosine Kinase 1 (SPHK1))
- Abstract
- SPHK1 Produkte
- Synonyme
- CG1747 antikoerper, Dmel\\CG1747 antikoerper, SK1 antikoerper, Sphk1 antikoerper, SPHK1 antikoerper, F18E5.160 antikoerper, F18E5_160 antikoerper, sphingosine kinase 1 antikoerper, SPHK antikoerper, 1110006G24Rik antikoerper, Sk1 antikoerper, Spk1 antikoerper, Sphingosine kinase 1 antikoerper, sphingosine kinase 1 antikoerper, sphingosine kinase 1 L homeolog antikoerper, Sk1 antikoerper, SPHK1 antikoerper, sphk1.L antikoerper, Sphk1 antikoerper
- Hintergrund
- Activation of Sphingosine kinase (Sphk) increases the bioactive lipid, sphingosine 1-phosphate (S1P) and has been observed in a variety of cancer cells. Phosphorylation of sphingosine by sphingosine kinase (Sphk) is the rate-limiting step in the cellular synthesis of S1P. A principle activation event is the phosphorylation of serine 225 of sphiongosine kinase 1. Inhibition of Sphk1 phosphorylation and hence, Sphk activity is an important target for the development of drugs for cancer, inflammation, cardioprotection as well as a many other indications.Synonyms: SPHK, SPK, SPK 1, SPK-1
- Gen-ID
- 20698
- NCBI Accession
- NP_001165943
- UniProt
- Q8CI15
- Pathways
- VEGF Signaling
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