Histone Deacetylase 1 (HDAC1) Antikörper

Antigen: Histone Deacetylase 1 (HDAC1)

Synonyme: HD1, RPD3, GON-10, RPD3L1, DKFZp686H12203, Hdac1, Gm1824, EG15181, Hdac1-ps, ENSMUSG00000061062, CG7471, dHDAC-1, dHDAC1, DHDAC1, DmelCG7471, dmHDA401, DmHDAC1, drpd3, dRpd3, dRPD3, DRpd3, E(var)3-64BC, HDAC, HDAC-1, hdac1, HDAC1, l(3)04556, l(3)64Cc, rpd3, Rpd3/HDAC, rpd[3], Su(var)3-26, Su(var)326, Su(var)328, hdac1b, MGC53583, Rpd3, GB14706, yaf1, MGC69271, MGC81850, gon-10, rpd3l1, hdac1-b, MGC69289, hdac-1, MGC101582, chunp6919, zgc:65818, wu:fb19h11, wu:fi06f03, zgc:101582, mp:zf637-2-001987, MGC127235, MommeD5, MGC102534, MGC118085, ARABIDOPSIS HISTONE DEACETYLASE 1, ATHD1, ATRPD3A, F20D10.250, F20D10_250, HDA1, HDA19, HISTONE DEACETYLASE, HISTONE DEACETYLASE 1, HISTONE DEACETYLASE 19, HISTONE DEACETYLASE19, RPD3A, DKFZp468K082

Klonalität: Polyklonal

Wirt: Kaninchen

Reaktivität: Human, Ratte (Rattus)

Applikation: Immunhistochemie (IHC)

Produktnummer: ABIN461656

Produktbeschreibung

Weitere Bezeichnung: HDAC1

Format: Liquid

Beschreibung: In the intact cell, DNA closely associates with histones and other nuclear proteins to form chromatin. The remodeling of chromatin is believed to be a critical component of transcriptional regulation and a major source of this remodeling is brought about by the acetylation of nucleosomal histones. Acetylation of lysine residues in the amino-terminal tail domain of histone results in an allosteric change in the nucleosomal conformation and an increased accessibility to transcription factors by DNA. Conversely, the deacetylation of histones is associated with transcriptional silencing. Several mammalian proteins have been identified as nuclear histone acetylases, including GCN5, PCAF (for p300/CBP-associated factor), p300/CBP and the TFIID subunit TAF II p250. Mammalian HDAC1 (also designated HD1), HDAC2 (also designated mammalian RPD3) and HDAC3, all of which are related to the yeast transcriptional regulator Rpd3p, have been identified as histone deacetylases.
Synonyms: HDAC1, DKFZP686H12203, GON-10, HD1, RPD3, RPD3L1

Spezifität: HDAC1 (E427) pAb detects endogenous levels of HDAC1 protein.

Synonyme: HD1, RPD3, GON-10, RPD3L1, DKFZp686H12203, Hdac1, Gm1824, EG15181, Hdac1-ps, ENSMUSG00000061062, CG7471, dHDAC-1, dHDAC1, DHDAC1, DmelCG7471, dmHDA401, DmHDAC1, drpd3, dRpd3, dRPD3, DRpd3, E(var)3-64BC, HDAC, HDAC-1, hdac1, HDAC1, l(3)04556, l(3)64Cc, rpd3, Rpd3/HDAC, rpd[3], Su(var)3-26, Su(var)326, Su(var)328, hdac1b, MGC53583, Rpd3, GB14706, yaf1, MGC69271, MGC81850, gon-10, rpd3l1, hdac1-b, MGC69289, hdac-1, MGC101582, chunp6919, zgc:65818, wu:fb19h11, wu:fi06f03, zgc:101582, mp:zf637-2-001987, MGC127235, MommeD5, MGC102534, MGC118085, ARABIDOPSIS HISTONE DEACETYLASE 1, ATHD1, ATRPD3A, F20D10.250, F20D10_250, HDA1, HDA19, HISTONE DEACETYLASE, HISTONE DEACETYLASE 1, HISTONE DEACETYLASE 19, HISTONE DEACETYLASE19, RPD3A, DKFZp468K082

Anwendungen

Applikationshinweise: IHC: 1:50-1:200

Konzentration: 1 mg/ml

Reinheit: > 95% (by SDS-PAGE).

Reinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Buffer: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.

Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Bilder

anti-Histone Deacetylase 1 (HDAC1) antibody