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Antikörper
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anti-H2A Histone Family, Member X (H2AFX) Antikörper
H2A Histone Family, Member X (H2AFX) Antikörper
| Antigen |
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| Synonyme |
H2AX, H2A.X, H2A/X, H2ax, AW228881, Hist5-2ax, h2afx, MGC82078 |
| Klonalität |
Polyklonal |
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Wirt
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Reaktivität
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Human (87), Maus (47), Ratte (Rattus) (39), Rind (Kuh) (20), Hund (19), Pferd (17), Schwein (17), Kaninchen (17), Huhn (4), Affe (2), Meerschweinchen (1), Hamster (1), Schaf (1)
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Applikation
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Western Blot (WB) (66), Immunfluoreszenz (IF) (51), Durchflusszytometrie (FACS) (20), Immunhistochemie (Paraffinschnitte) (IHC (p)) (14), Immunhistochemie (IHC) (9), ELISA (8), Immunpräzipitation (IP) (8), Enzyme Immunoassay (EIA) (6), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (5), Immunhistochemie (formalinfixierte Schnitte) (IHC (f)) (2), Dot Blot (Dot) (1), ELISA (Detektionsantikörper) (1), Immunoelectron Microscopy (IEM) (1)
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| Produktnummer |
ABIN461604 |
| Menge |
100µg (1 mg/ml) (Varianten) |
| Preis |
572,09 € Zzgl. Versandkosten €20,00 und MWSt
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| Lieferung nach |
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| Verfügbarkeit |
Lieferung in 7 bis 10 Werktagen |
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Weitere Bezeichnung
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Histone H2A.X
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Format
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Liquid
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Beschreibung
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H2A.X is a member of the histone H2A family, 1 of 5 families of histone proteins involved in nucleosomal organization of chromatin. H2A.X is synthesised in G1 as well as S phase and is known to be important for recombination between immunoglobulin switch regions. A very early step in the response of mammalian cells to DNA double-strand breaks is the phosphorylation of histone H2A.X at serine 139 at the sites of DNA damage. There is a predicted acetylation at residue 1 and ubiquitination at reside 119. Phosphorylated H2A.X promotes DNA repair and maintains genomic stability.
Synonyms: H2a/x, Histone H2A.X, H2AX
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Spezifität
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Histone H2A.X (E145) pAb detects endogenous levels of Histone H2A.X protein.
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Molekulargewicht
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15 kDa
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Applikationshinweise
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WB: 1:500-1:1000 IHC: 1:50-1:200
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Konzentration
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1 mg/ml
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Reinheit
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> 95% (by SDS-PAGE).
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Reinigung
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The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Buffer
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1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
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Lagerung
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
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Beschränkungen
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Nur für Forschungszwecke einsetzbar
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Alternativen zu Antigen "H2A Histone Family, Member X (H2AFX)", Typ "Antikörper" finden
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Wirte
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Kaninchen (82), Maus (9)
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Reaktivitäten
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Human (87), Maus (47), Ratte (Rattus) (39), Rind (Kuh) (20), Hund (19), Pferd (17), Schwein (17), Kaninchen (17), Huhn (4), Affe (2), Meerschweinchen (1), Hamster (1), Schaf (1)
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Applikationen
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Western Blot (WB) (66), Immunfluoreszenz (IF) (51), Durchflusszytometrie (FACS) (20), Immunhistochemie (Paraffinschnitte) (IHC (p)) (14), Immunhistochemie (IHC) (9), ELISA (8), Immunpräzipitation (IP) (8), Enzyme Immunoassay (EIA) (6), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (5), Immunhistochemie (formalinfixierte Schnitte) (IHC (f)) (2), Dot Blot (Dot) (1), ELISA (Detektionsantikörper) (1), Immunoelectron Microscopy (IEM) (1)
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Konjugate
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FITC (2), Alexa Flour 488 (1), Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1), RBITC (1)
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Epitope
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pSer139 (18)
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Alternativen 
