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Antikörper
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anti-Forkhead Box O1 (FOXO1) Antikörper
Forkhead Box O1 (FOXO1) Antikörper
| Antigen |
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| Synonyme |
FKH1, FKHR, FOXO1A, Afxh, Fkhr1, Foxo1a, AI876417, Fkhr, FOXO1, fkh1, fkhr, foxo1a, xFoxO1, MGC79506 |
| Klonalität |
Polyklonal |
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Wirt
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Reaktivität
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Applikation
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Western Blot (WB) (124), Immunfluoreszenz (IF) (46), Immunhistochemie (IHC) (40), Immunhistochemie (Paraffinschnitte) (IHC (p)) (32), Durchflusszytometrie (FACS) (19), ELISA (18), Enzyme Immunoassay (EIA) (17), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (10), Immunpräzipitation (IP) (6), Dot Blot (Dot) (2), Immunzytochemie (ICC) (2), Immunhistochemie (formalinfixierte Schnitte) (IHC (f)) (2), Immunoelectron Microscopy (IEM) (1)
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| Produktnummer |
ABIN461599 |
| Menge |
100µg (1 mg/ml) (Varianten) |
| Preis |
572,09 € Zzgl. Versandkosten €20,00 und MWSt
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| Lieferung nach |
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| Verfügbarkeit |
Lieferung in 7 bis 10 Werktagen |
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Weitere Bezeichnung
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FKHR/FOXO1A
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Format
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Liquid
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Beschreibung
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FKHR (for forkhead in rhabdomyosarcoma) and FKHRL1 are members of the forkhead family of transcription factors. Transcriptional activation of FKHR proteins is regulated by the serine/threonine kinase Akt1, which phosphorylates FKHRL1 and results in FKHRL1 associating with 14-3-3 proteins and being retained in the cytoplasm. Induction of apoptosis or withdrawal of growth factors stimulates dephosphorylation and nuclear translocation of FKHR proteins, leading to FKHR-induced gene-specific transcriptional activation. FKHR, also designated forkhead box protein O1A (FOXO1), is an ubiquitously expressed protein that shuttles between the cytoplasm and nucleus. Genetic mutations in FKHR genes, including the t(2,13) and t(1,3) translocations, are commonly found in alveolar rhabdomyosarcomas.
Synonyms: Forkhead in rhabdomyosarcoma, FKHR/FOXO1A, FKHR
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Spezifität
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FKHR/FOXO1A (I325) pAb detects endogenous levels of FKHR/FOXO1A protein.
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Molekulargewicht
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82 kDa
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Applikationshinweise
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WB: 1:500-1:1000 IHC: 1:50-1:200
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Konzentration
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1 mg/ml
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Reinheit
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> 95% (by SDS-PAGE).
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Reinigung
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The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Buffer
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1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
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Lagerung
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
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Beschränkungen
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Nur für Forschungszwecke einsetzbar
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Alternativen zu Antigen "Forkhead Box O1 (FOXO1)", Typ "Antikörper" finden
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Wirte
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Kaninchen (110), Maus (36), Ziege (5)
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Reaktivitäten
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Human (150), Maus (80), Ratte (Rattus) (71), Rind (Kuh) (21), Hund (21), Schwein (19), Huhn (2), Affe (2)
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Applikationen
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Western Blot (WB) (124), Immunfluoreszenz (IF) (46), Immunhistochemie (IHC) (40), Immunhistochemie (Paraffinschnitte) (IHC (p)) (32), Durchflusszytometrie (FACS) (19), ELISA (18), Enzyme Immunoassay (EIA) (17), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (10), Immunpräzipitation (IP) (6), Dot Blot (Dot) (2), Immunzytochemie (ICC) (2), Immunhistochemie (formalinfixierte Schnitte) (IHC (f)) (2), Immunoelectron Microscopy (IEM) (1)
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Konjugate
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Alexa Flour 488 (1), Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1), RBITC (1)
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Epitope
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pSer256 (10), pSer319 (9), AA 242-655 (1), Ab-329 (1), Center (1), Center D469 (1), pSer329 (1)
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Alternativen 
