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B-Cell CLL/lymphoma 2 (BCL2) Antikörper

Antigen

B-Cell CLL/lymphoma 2 (BCL2)
Synonyme Bcl-2, bcl-2, BCL2
Klonalität Polyklonal
Wirt
Alternativen

Kaninchen
Reaktivität
Alternativen

Human
Applikation
Alternativen Western Blot (WB), Immunhistochemie (IHC), Immunfluoreszenz (IF)
Produktnummer ABIN461151
Menge 100µg  (1 mg/ml)  (Varianten)
Preis 572,09 €   Zzgl. Versandkosten €20,00 und MWSt
Lieferung nach
Verfügbarkeit Lieferung in 7 bis 10 Werktagen

anti-B-Cell CLL/lymphoma 2 (BCL2) antibody

anti-B-Cell CLL/lymphoma 2 (BCL2) antibody (2)

Produktbeschreibung
Anwendungen Bilder Alternativen Sekundärantikörper Varianten zurück nach oben

Weitere Bezeichnung Bcl-2
Format Liquid
Beschreibung Apoptosis defines a set of cascades which, when initiated, programs the cell to undergo lethal changes such as membrane blebbing, mitochondrial break down and DNA fragmentation. Bcl-2 is one among many key regulators of apoptosis which are essential for proper development, tissue homeostasis and protection against foreign pathogens. Human Bcl-2 is a 26 kD,a membraneassociated, anti-apoptotic oncoprotein that can promote cell survival through protein-protein interactions with other Bcl-2 related family members, such as the death suppressors Bcl-xL, Mcl-1, Bcl-w and A1, or the death agonists Bax, Bak, Bik, Bad and BID. The anti-apoptotic function of Bcl-2 can also beregulated through proteolytic processing and phosphorylation. Bcl-2 may promote cell survival by interfering with the activation of the cytochrome c/Apaf-1 pathway through stabilization of the mitochondrial membrane. Mutations in the Bcl-2 gene can contribute to cancers where normal physiological cell death mechanisms are compromised by deregulation of the antiapoptotic influence of Bcl-2.
Synonyms: IgG Fraction of Anti-Human Bcl-2 (Rabbit), BCL2
Spezifität Bcl-2 (S50) pAb detects endogenous levels of Bcl-2 protein.
Molekulargewicht 26 kDa

Anwendungen
Bilder Alternativen Sekundärantikörper Varianten zurück nach oben

Applikationshinweise WB: 1:500-1:1000 IHC: 1:50-1:200 IF: 1:50-1:200
Konzentration 1 mg/ml
Reinheit > 95% (by SDS-PAGE).
Reinigung The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Buffer 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Lagerung Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Beschränkungen Nur für Forschungszwecke einsetzbar

Alternativen
Anwendungen Bilder Sekundärantikörper Varianten zurück nach oben

Alternativen zu Antigen "B-Cell CLL/lymphoma 2 (BCL2)", Typ "Antikörper" finden
Wirte Kaninchen (141), Maus (50), Ziege (5), Schaf (4)
Reaktivitäten Human (180), Maus (76), Ratte (Rattus) (74), Hund (38), Rind (Kuh) (37), Schwein (35), Kaninchen (22), Huhn (18), Pferd (18), Schaf (3), Katze (2), Affe (2), Hamster (1)
Applikationen Western Blot (WB) (133), Immunfluoreszenz (IF) (73), Immunhistochemie (Paraffinschnitte) (IHC (p)) (58), Immunpräzipitation (IP) (56), Durchflusszytometrie (FACS) (50), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (40), Immunhistochemie (IHC) (38), ELISA (26), Enzyme Immunoassay (EIA) (21), Immunhistochemie (formalinfixierte Schnitte) (IHC (f)) (4), Immunzytochemie (ICC) (3), Dot Blot (Dot) (2), Immunoelectron Microscopy (IEM) (2), Intrazelluläre Durchflusszytometrie (ICFC) (2)
Konjugate PE (3), Alexa Flour 488 (2), Alexa Fluor 350 (2), Alexa Fluor 488 (2), Alexa Fluor 555 (2), Alexa Fluor 647 (2), Biotin (2), Cy3 (2), Cy5 (2), Cy5.5 (2), Cy7 (2), FITC (2), Gold (2), HRP (2), PE,Cy3 (2), PE,Cy5 (2), PE,Cy5.5 (2), PE,Cy7 (2), RBITC (2)
Epitope pThr56 (7), pSer70 (5), BH3 Domain Specific (1)