Myeloid Differentiation Primary Response Gene (88) (MYD88) Antikörper

Antigen: Myeloid Differentiation Primary Response Gene (88) (MYD88)

Synonyme: MYD88D, XMyD88, myd88d, MGC84928, DMMYD88, EP(2)2535, Kra, LD20892, MYD88, dMyD88, DmelCG2078, CG2078, zgc:103541, GB12344, NV10640, myd88, IRAK-2, MGC150550, AI649099, MGC102586, 6330415L08Rik, irak-2, MGC79591, IRAK2

Klonalität: Polyklonal

Wirt: Kaninchen

Reaktivität: Human, Ratte (Rattus)

Applikation: Western Blot (WB), Immunhistochemie (IHC)

Produktnummer: ABIN460993

Produktbeschreibung

Weitere Bezeichnung: MyD88

Format: Liquid

Beschreibung: Interleukin-1 (IL-1)-induced activation of the NFkappaB pathway is mediated through the IL-1 receptor and the subsequent phosphorylation of IL-1 receptorassociated kinase (IRAK). The myeloid differentiation protein MyD88 was originally characterized as a protein upregulated in myeloleukemic cells following IL-6-induced growth arrest and terminal differentiation. MyD88 is now known to function as an adaptor protein for the association of IRAK with the IL-1 receptor. MyD88 is functionally homologous to the adaptor protein tube in the Toll signaling pathway of Drosophilia, and both proteins are members of the Toll/IL-1R superfamily. MyD88 contains a characteristic N-terminal death domain that is essential for NFkappaB activation and an adjacent Toll/IL-1R homology domain (TIR domain). Collectively, these domains enable the protein-protein interactions of MyD88 with IRAK and the IL-1 receptor complex.
Synonyms: myeloid differentiation primary response gene 88, . Entrez Gene ID: 4615

Spezifität: MyD88 (V220) pAb detects endogenous levels of MyD88 protein.

Molekulargewicht: 33 kDa

Synonyme: MYD88D, XMyD88, myd88d, MGC84928, DMMYD88, EP(2)2535, Kra, LD20892, MYD88, dMyD88, DmelCG2078, CG2078, zgc:103541, GB12344, NV10640, myd88, IRAK-2, MGC150550, AI649099, MGC102586, 6330415L08Rik, irak-2, MGC79591, IRAK2

Anwendungen

Applikationshinweise: WB: 1:500-1:1000 IHC: 1:50-1:200

Konzentration: 1 mg/ml

Reinheit: > 95% (by SDS-PAGE).

Reinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Buffer: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.

Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Bilder

anti-Myeloid Differentiation Primary Response Gene (88) (MYD88) antibody

anti-Myeloid Differentiation Primary Response Gene (88) (MYD88) antibody (Image 2)