Glutamate Receptor, Ionotrophic, AMPA 2/3 (GRIA2/3) Antikörper

Antigen: Glutamate Receptor, Ionotrophic, AMPA 2/3 (GRIA2/3)

Synonyme: GLUH1, GLUR1, GLURA, HBGR1, MGC133252, GLUR2, GLURB, HBGR2, GluR-K2, Glr1, Glr-1, GluA1, GluRA, Glur1, HIPA1, GluR-A, Glur-1, AI853806, 2900051M01Rik, GluA2, Glur2, GluR-B, Glur-2, GluR2, gluR-B, gluR-A

Klonalität: Polyklonal

Wirt: Kaninchen

Reaktivität: Human, Ratte (Rattus)

Applikation: Western Blot (WB), Immunhistochemie (IHC)

Produktnummer: ABIN460915

Produktbeschreibung

Weitere Bezeichnung: mGluR-2/3

Format: Liquid

Beschreibung: The mGluR proteins (metabotropic glutamate receptors) are members of the G-protein-coupled receptor family and are functionally and pharmacologically distinct from the GluR proteins (ionotropic glutamate receptors). The eight currently known mGluR proteins are mediated by two G proteins with opposing regulation of adenylate cyclase pathways. The activities of mGluR-1 and mGluR-5 are mediated by a G protein that activates a phosphatidylinositolcalcium second messenger system and generates a calcium-activated chloride current. The remainder of the eight subtypes of mGluR have an activity mediated by a G protein that inhibits adenylate cyclase activity. mGluR-2, which may interact with GRASP, acts as a receptor for glutamate. It may also be involved in the regulation of neurotransmission suppression and in synaptogenesis or synaptic stablization. mGluR-3,which may interact with GRASP, acts as a receptor for glutamate.
Synonyms: mGluR2, GRM2, GPRC1B, MGLUR2, GLUR2, mGlu2

Spezifität: MGluR2/3 (N867) pAb detects endogenous levels of mGluR2/3 protein.

Synonyme: GLUH1, GLUR1, GLURA, HBGR1, MGC133252, GLUR2, GLURB, HBGR2, GluR-K2, Glr1, Glr-1, GluA1, GluRA, Glur1, HIPA1, GluR-A, Glur-1, AI853806, 2900051M01Rik, GluA2, Glur2, GluR-B, Glur-2, GluR2, gluR-B, gluR-A

Anwendungen

Applikationshinweise: WB: 1:500-1:1000 IHC: 1:50-1:200

Konzentration: 1 mg/ml

Reinheit: > 95% (by SDS-PAGE).

Reinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Buffer: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.

Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Bilder

anti-Glutamate Receptor, Ionotrophic, AMPA 2/3 (GRIA2/3) antibody

anti-Glutamate Receptor, Ionotrophic, AMPA 2/3 (GRIA2/3) antibody (Image 2)