A Kinase (PRKA) Anchor Protein 1 (AKAP1) Antikörper

Antigen: A Kinase (PRKA) Anchor Protein 1 (AKAP1)

Synonyme: AKAP, PRKA1, AKAP84, AKAP121, AKAP149, D-AKAP1, MGC1807, SAKAP84, Akap, C76494, C81186, DAKAP1, S-AKAP84, AKAP1, akap1, fa08b04, MGC162884, wu:fa08b04, Akap84

Klonalität: Polyklonal

Wirt: Kaninchen

Reaktivität: Human

Applikation: Western Blot (WB), Immunhistochemie (IHC), Immunfluoreszenz (IF)

Produktnummer: ABIN460541

Produktbeschreibung

Weitere Bezeichnung: AKAP 149

Format: Liquid

Beschreibung: The type II cAMP-protein kinase (PKA) is a multifunctional kinase with a broad range of substrates. Specificity of PKA signaling is thought to be mediated by the compartmentalization of the kinase to specific sites within the cell. To maintain this specific localization, the R subunit (RII) of PKA interacts with specific RII-anchoring proteins. This family of proteins has been designated A-kinase anchoring proteins (AKAP). Members of this family, including MAP2 (microtubule-associated protein 2), neuronally expressed AKAP 79 and AKAP 150, and the DNA binding AKAP 95, display differential tissue specificity and localization. Evidence suggests that AKAP 79 and AKAP 150 are both capable of anchoring PKA to postsynaptic densities (PSD), which are a network of proteins located on the internal surfaces of excitatory synapses.
Synonyms: AKAP1

Spezifität: AKAP 149(N306) pAb detects endogenous levels of AKAP 149 protein.

Molekulargewicht: 90 kDa

Anwendungen

Applikationshinweise: WB: 1:500-1:1000 IHC: 1:50-1:200 IF: 1:50-1:200

Konzentration: 1 mg/ml

Reinheit: > 95% (by SDS-PAGE).

Reinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Buffer: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.

Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Bilder

anti-A Kinase (PRKA) Anchor Protein 1 (AKAP1) antibody

anti-A Kinase (PRKA) Anchor Protein 1 (AKAP1) antibody (Image 2)