In den Warenkorb
Bestellen Sie auch über:
 |
+49 (0)241 95 163 153 |
 |
+49 (0)241 95 163 155 |
V-Akt Murine Thymoma Viral Oncogene Homolog 1 (AKT1) Antikörper
| Antigen | V-Akt Murine Thymoma Viral Oncogene Homolog 1 (AKT1) |
| Synonyme |
AKT, PKB, RAC, PRKBA, MGC99656, PKB-ALPHA, RAC-ALPHA, Akt, pkb, xAct, akt-1, v-akt, v-akt1, AKT1, AKT/PKB, D-Akt, DAKT1, DAKT1/PKB, DPKB, DRAC-PK, DRAC-PK66; DRAC-PK85, Dakt, PKB/AKT, PKB/dAKT, RacPK, ...
mehr anzeigen
|
| Klonalität | Polyklonal |
| Wirt |
 Alternativen Kaninchen |
| Reaktivität |
Alternativen Human, Ratte (Rattus) |
| Applikation |
Alternativen Western Blot (WB)
|
| Produktnummer | ABIN460159 |
| Menge | 100µg (1 mg/ml) (Varianten) |
| Preis | 572,09 € Zzgl. Versandkosten €20,00 und MWSt |
| Lieferung nach |
|
| Verfügbarkeit | Lieferung in 7 bis 10 Werktagen |
Produktbeschreibung
| Weitere Bezeichnung | Akt |
| Format | Liquid |
| Beschreibung |
AKT, also known as protein kinase B (PKB), is a 57 kDa serine/threonine protein kinase. There are three mammalian isoforms of Akt: AKT1 (PKB alpha), AKT2 (PKB beta) and AKT3 (PKB gamma) with AKT2 and AKT3 being approximately 82% identical with the AKT1 isoform. Each isoform has a pleckstrin homology (PH) domain, a kinase domain and a carboxy terminal regulatory domain. AKT was originally cloned from the retrovirus AKT8, and is a key regulator of many signal transduction pathways. Its tight control over cell proliferation and cell viability are manifold, overexpression or inappropriate activation of AKT has been seen in many types of cancer. AKT mediates many of the downstream events of phosphatidylinositol 3 kinase (a lipid kinase activated by growth factors, cytokines and insulin). Synonyms: Protein kinase B alpha (PRK-BA), Serine/Threonine specific kinase RAC alpha, Protein kinase Akt |
| Spezifität | Akt (M118) pAb detects endogenous levels of Akt protein. |
| Molekulargewicht | 55 kDa |
| Synonyme | AKT, PKB, RAC, PRKBA, MGC99656, PKB-ALPHA, RAC-ALPHA, Akt, pkb, xAct, akt-1, v-akt, v-akt1, AKT1, AKT/PKB, D-Akt, DAKT1, DAKT1/PKB, DPKB, DRAC-PK, DRAC-PK66; DRAC-PK85, Dakt, PKB/AKT, PKB/dAKT, RacPK, dAKT/dPKB, dAkt/PKB, l(3)04226, l(3)89Bq, DmelCG4006, CG4006 |
Anwendungen
| Applikationshinweise | WB: 1:500-1:1000 |
| Konzentration | 1 mg/ml |
| Reinheit | > 95% (by SDS-PAGE). |
| Reinigung | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Buffer | 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2. |
| Lagerung | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. |
| Beschränkungen | Nur für Forschungszwecke einsetzbar |
Alternativen
Alternativen zu Antigen "V-Akt Murine Thymoma Viral Oncogene Homolog 1 (AKT1)", Typ "Antikörper" finden
| Wirte | Kaninchen (232), Maus (74), Huhn (4), Schaf (4) |
| Reaktivitäten | Human (295), Maus (158), Ratte (Rattus) (151), Huhn (12), Hund (12), Affe (6), Rind (Kuh) (3), Schimpanse (2), Schaf (2), Xenopus laevis (2), Schwein (1) |
| Applikationen | Western Blot (WB) (261), Immunhistochemie (IHC) (80), Enzyme Immunoassay (EIA) (77), Immunhistochemie (Paraffinschnitte) (IHC (p)) (74), Immunfluoreszenz (IF) (72), ELISA (48), Immunpräzipitation (IP) (29), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (25), Durchflusszytometrie (FACS) (12), Dot Blot (Dot) (9), Immunzytochemie (ICC) (3), Konjugation (1), ELISA (Detektionsantikörper) (1), Funktionale Studien (Func) (1) |
| Konjugate | Biotin (3), APC (1), CF (1), HRP (1), PE (1) |
| Epitope | pSer473 (29), pThr308 (18), pThr450 (5), pTyr315/316/312 (4), S129 (3), pS473 (3), C-Term (2), N-Term (2), S246 (2), pS124 (2), pThr308/309 (2), pTyr326 (2), pY326 (2), N-Term G37 (1), S124 (1), S473 (1), pSer124 (1), pSer129 (1), pT308 (1) |
