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P21 Protein (Cdc42/Rac)-Activated Kinase 1 (PAK1) Antikörper
| Antigen | P21 Protein (Cdc42/Rac)-Activated Kinase 1 (PAK1) |
| Klonalität | Polyklonal |
| Wirt |
 Alternativen Kaninchen |
| Reaktivität |
Alternativen Human, Ratte (Rattus) |
| Applikation |
Alternativen Western Blot (WB), Immunhistochemie (IHC), Immunfluoreszenz (IF)
|
| Produktnummer | ABIN460151 |
| Menge | 100µg (1 mg/ml) (Varianten) |
| Preis | 572,09 € Zzgl. Versandkosten €20,00 und MWSt |
| Lieferung nach |
|
| Verfügbarkeit | Lieferung in 7 bis 10 Werktagen |
Produktbeschreibung
| Weitere Bezeichnung | PAKalpha |
| Format | Liquid |
| Beschreibung |
The serine/threonine kinase Pak1 is an effector of small Rho GTPases, Rac1 and Cdc42. Pak1 complex specifically with Rac1 and Cdc42 in their active GTP bound state, inhibiting their intrinsic GTPase activity leading to their autophosphorylation. It plays an important role in the regulation of cell morphogenesis, motility, mitosis, and angiogenesis and has been implicated in the progression of many cancers Synonyms: AW045634, Alpha PAK, CDC42/RAC effector kinase PAK A, CDC42/RAC effector kinase PAKA, EC 2.7.11.1 , MGC130000, MGC130001, PAK 1, PAK alpha, PAKalpha, Paka, Protein kinase MUK2 , STE20 homolog (yeast), Serine/threonine protein kinase PAK 1, Serine/threonin |
| Spezifität | PAKalpha (E195) pAb detects endogenous levels of PAKalpha protein. |
| Molekulargewicht | 61 kDa |
Anwendungen
| Applikationshinweise | WB: 1:500-1:1000 IHC: 1:50-1:200 IF: 1:50-1:200 |
| Konzentration | 1 mg/ml |
| Reinheit | > 95% (by SDS-PAGE). |
| Reinigung | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Buffer | 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2. |
| Lagerung | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. |
| Beschränkungen | Nur für Forschungszwecke einsetzbar |
Bilder
| anti-P21 Protein (Cdc42/Rac)-Activated Kinase 1 (PAK1) antibody anti-P21 Protein (Cdc42/Rac)-Activated Kinase 1 (PAK1) antibody (Image 2) |
Alternativen
Alternativen zu Antigen "P21 Protein (Cdc42/Rac)-Activated Kinase 1 (PAK1)", Typ "Antikörper" finden
| Wirte | Kaninchen (3) |
| Reaktivitäten | Human (3), Ratte (Rattus) (1) |
| Applikationen | Western Blot (WB) (2), Enzyme Immunoassay (EIA) (1), Immunhistochemie (IHC) (1), Immunpräzipitation (IP) (1) |
| Epitope | pSer20 (1), pThr423 (1) |
