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Antikörper
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anti-V-Crk Sarcoma Virus CT10 Oncogene Homolog (Avian)-Like (CRKL) Antikörper
V-Crk Sarcoma Virus CT10 Oncogene Homolog (Avian)-Like (CRKL) Antikörper
| Antigen |
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| Synonyme |
Crkol, AA589403, AI325100, 1110025F07Rik, CRKL, MGC63469, zgc:63469, wu:fa55g05, wu:fj60e01 |
| Klonalität |
Polyklonal |
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Wirt
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Reaktivität
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Applikation
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 Alternativen Western Blot (WB), Immunhistochemie (IHC), Immunfluoreszenz (IF)
Western Blot (WB) (29), ELISA (7), Immunhistochemie (IHC) (7), Immunfluoreszenz (IF) (6), Enzyme Immunoassay (EIA) (5), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (4), Immunhistochemie (Paraffinschnitte) (IHC (p)) (4), ELISA (Detektionsantikörper) (3), Immunpräzipitation (IP) (3), Immunzytochemie (ICC) (2), Dot Blot (Dot) (1), Durchflusszytometrie (FACS) (1)
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| Produktnummer |
ABIN460079 |
| Menge |
100µg (1 mg/ml) (Varianten) |
| Preis |
572,09 € Zzgl. Versandkosten €20,00 und MWSt
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| Lieferung nach |
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| Verfügbarkeit |
Lieferung in 7 bis 10 Werktagen |
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Weitere Bezeichnung
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CrkL
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Format
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Liquid
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Beschreibung
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SH2 and SH3 (Src homology) domains were originally identified as critical functional domains within non-receptor proteins with tyrosine kinase activity. A subset of these proteins appears to exist predominately of SH2/SH3 domains in the absence of detectable catalytic domains. One of the first members of the family to be identified, Crk, is a transformation-specific protein that induces elevation of cellular phosphotyrosine levels, but lacks tyrosine kinase activity itself. A second protein, Nck, consists solely of three SH3 domains and one SH2 domain, while GRB2 contains an SH2 domain flanked on both sides by SH3 domains. A member of this protein class, Crk-L, is encoded by a gene located on chromosome 22, band 11, centromeric of the chronic myelogenous leukemia breakpoint region. Crk-L encodes a 303 amino acid protein with one SH2 and two SH3 domains, and a predicted molecular weight of 36 kDa.
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Spezifität
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CrkL (P201) pAb detects endogenous levels of CrkL protein.
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Molekulargewicht
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39 kDa
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Applikationshinweise
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WB: 1:500-1:1000 IHC: 1:50-1:200 IF:1:50-1:200
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Konzentration
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1 mg/ml
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Reinheit
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> 95% (by SDS-PAGE).
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Reinigung
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The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Buffer
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1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
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Lagerung
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
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Beschränkungen
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Nur für Forschungszwecke einsetzbar
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Alternativen zu Antigen "V-Crk Sarcoma Virus CT10 Oncogene Homolog (Avian)-Like (CRKL)", Typ "Antikörper" finden
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Wirte
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Kaninchen (20), Ziege (7), Maus (6)
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Reaktivitäten
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Human (30), Maus (10), Ratte (Rattus) (7), Hund (1)
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Applikationen
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Western Blot (WB) (29), ELISA (7), Immunhistochemie (IHC) (7), Immunfluoreszenz (IF) (6), Enzyme Immunoassay (EIA) (5), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (4), Immunhistochemie (Paraffinschnitte) (IHC (p)) (4), ELISA (Detektionsantikörper) (3), Immunpräzipitation (IP) (3), Immunzytochemie (ICC) (2), Dot Blot (Dot) (1), Durchflusszytometrie (FACS) (1)
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Epitope
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pTry207 (23), pTyr207 (1)
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