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Antikörper
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anti-Histone Deacetylase 10 (HDAC10) Antikörper
Histone Deacetylase 10 (HDAC10) Antikörper
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| Synonyme |
MGC149722, DKFZp761B039, Hd10, AW548891, HDAC10, MGC139128, fd19e10, wu:fd19e10, MGC115178, histone deacetylase 10 |
| Klonalität |
Polyklonal |
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Wirt
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Reaktivität
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Applikation
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Western Blot (WB) (47), Durchflusszytometrie (FACS) (30), Immunfluoreszenz (IF) (24), Immunhistochemie (IHC) (21), ELISA (9), Enzyme Immunoassay (EIA) (7), Immunhistochemie (Paraffinschnitte) (IHC (p)) (3), Immunpräzipitation (IP) (3), Immunhistochemie (formalinfixierte Schnitte) (IHC (f)) (2), ELISA (Detektionsantikörper) (1), Immunzytochemie (ICC) (1), Immunoelectron Microscopy (IEM) (1), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (1)
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| Produktnummer |
ABIN459549 |
| Menge |
100µg (1 mg/ml) (Varianten) |
| Preis |
572,09 € Zzgl. Versandkosten €20,00 und MWSt
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| Lieferung nach |
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| Verfügbarkeit |
Lieferung in 7 bis 10 Werktagen |
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Weitere Bezeichnung
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HDAC10
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Format
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Liquid
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Beschreibung
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In the intact cell, DNA closely associates with histones and other nuclear proteins to form chromatin. The remodeling of chromatin is believed to be a critical component of transcriptional regulation and a major source of this remodeling is brought about by the acetylation of nucleosomal histones. Acetylation of lysine residues in the amino-terminal tail domain of histone results in an allosteric change in the nucleosomal conformation and an increased accessibility to transcription factors by DNA. Conversely, the deacetylation of histones is associated with transcriptional silencing. Several mammalian proteins have been identified as nuclear histone acetylases, including GCN5, PCAF (for p300/CBP-associated factor), p300/CBP and the TFIID subunit TAF II p250. Mammalian HDAC1 (also designated HD1), HDAC2 (also designated mammalian RPD3) and HDAC3, all of which are related to the yeast transcriptional regulator Rpd3p, have been identified as histone deacetylases.
Synonyms: HDAC10, DKFZP761B039, HD10
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Spezifität
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HDAC10 (E24) pAb detects endogenous levels of HDAC10 protein.
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Molekulargewicht
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75.0 kDa
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Applikationshinweise
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WB: 1:500-1:1000 IHC: 1:50-1:200
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Konzentration
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1 mg/ml
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Reinheit
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> 95% (by SDS-PAGE).
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Reinigung
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The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Buffer
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1 mg/ml in Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.2.
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Lagerung
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
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Beschränkungen
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Nur für Forschungszwecke einsetzbar
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Alternativen zu Antigen "Histone Deacetylase 10 (HDAC10)", Typ "Antikörper" finden
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Wirte
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Kaninchen (46), Maus (23)
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Reaktivitäten
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Human (51), Maus (24), Ratte (Rattus) (24), Rind (Kuh) (1), Hund (1), Kaninchen (1)
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Applikationen
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Western Blot (WB) (47), Durchflusszytometrie (FACS) (30), Immunfluoreszenz (IF) (24), Immunhistochemie (IHC) (21), ELISA (9), Enzyme Immunoassay (EIA) (7), Immunhistochemie (Paraffinschnitte) (IHC (p)) (3), Immunpräzipitation (IP) (3), Immunhistochemie (formalinfixierte Schnitte) (IHC (f)) (2), ELISA (Detektionsantikörper) (1), Immunzytochemie (ICC) (1), Immunoelectron Microscopy (IEM) (1), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (1)
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Konjugate
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Alexa Flour 488 (1), Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1), RBITC (1)
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Epitope
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transcript variant 1 (11), C-Term (2), N-Term (2)
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Alternativen 
