Histone Deacetylase 1 (HDAC1) Antikörper

Antigen: Histone Deacetylase 1 (HDAC1)

Synonyme: HD1, RPD3, GON-10, RPD3L1, DKFZp686H12203, Hdac1, Gm1824, EG15181, Hdac1-ps, ENSMUSG00000061062, CG7471, dHDAC-1, dHDAC1, DHDAC1, DmelCG7471, dmHDA401, DmHDAC1, drpd3, dRpd3, dRPD3, DRpd3, E(var)3-64BC, HDAC, HDAC-1, hdac1, HDAC1, l(3)04556, l(3)64Cc, rpd3, Rpd3/HDAC, rpd[3], Su(var)3-26, Su(var)326, Su(var)328, hdac1b, MGC53583, Rpd3, GB14706, yaf1, MGC69271, MGC81850, gon-10, rpd3l1, hdac1-b, MGC69289, hdac-1, MGC101582, chunp6919, zgc:65818, wu:fb19h11, wu:fi06f03, zgc:101582, mp:zf637-2-001987, MGC127235, MommeD5, MGC102534, MGC118085, ARABIDOPSIS HISTONE DEACETYLASE 1, ATHD1, ATRPD3A, F20D10.250, F20D10_250, HDA1, HDA19, HISTONE DEACETYLASE, HISTONE DEACETYLASE 1, HISTONE DEACETYLASE 19, HISTONE DEACETYLASE19, RPD3A, DKFZp468K082

Klonalität: Polyklonal

Wirt: Kaninchen

Reaktivität: Human, Ratte (Rattus)

Applikation: Western Blot (WB), Immunhistochemie (IHC), Immunfluoreszenz (IF)

Produktnummer: ABIN459548

Produktbeschreibung

Weitere Bezeichnung: HDAC1

Format: Liquid

Beschreibung: Reversible acetylation of highly conserved lysine residues within the N-terminal tail domains of core histones, plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone acetylation is a dynamic process determined by the net activities of histone acetyltransferases (HATs) and the competing enzymes histone deacetylases (HDACs). Histone deacetylases activities are often, but not always, associated with transcriptional repression and nucleosomal condensations. Recruitment of the multiprotein complexes to promoter sites occurs by many sequence specific DNA-binding proteins such as unliganded nuclear hormone receptors, DP1-E2F, YY1 and Rb family of transcription factors, transcriptional repressors and tumor suppressors (e.g. BRCA1). Aberrant recruitment of HDACs by certain oncoproteins may occur in certain neoplastic diseases.
Synonyms: HDAC1, DKFZP686H12203, GON-10, HD1, RPD3, RPD3L1

Spezifität: HDAC1(E468) pAb detects endogenous levels of HDAC1 protein.

Molekulargewicht: 55 kDa

Synonyme: HD1, RPD3, GON-10, RPD3L1, DKFZp686H12203, Hdac1, Gm1824, EG15181, Hdac1-ps, ENSMUSG00000061062, CG7471, dHDAC-1, dHDAC1, DHDAC1, DmelCG7471, dmHDA401, DmHDAC1, drpd3, dRpd3, dRPD3, DRpd3, E(var)3-64BC, HDAC, HDAC-1, hdac1, HDAC1, l(3)04556, l(3)64Cc, rpd3, Rpd3/HDAC, rpd[3], Su(var)3-26, Su(var)326, Su(var)328, hdac1b, MGC53583, Rpd3, GB14706, yaf1, MGC69271, MGC81850, gon-10, rpd3l1, hdac1-b, MGC69289, hdac-1, MGC101582, chunp6919, zgc:65818, wu:fb19h11, wu:fi06f03, zgc:101582, mp:zf637-2-001987, MGC127235, MommeD5, MGC102534, MGC118085, ARABIDOPSIS HISTONE DEACETYLASE 1, ATHD1, ATRPD3A, F20D10.250, F20D10_250, HDA1, HDA19, HISTONE DEACETYLASE, HISTONE DEACETYLASE 1, HISTONE DEACETYLASE 19, HISTONE DEACETYLASE19, RPD3A, DKFZp468K082

Anwendungen

Applikationshinweise: IF: 1:50-1:200 WB: 1:500-1:1000 IHC: 1:50-1:200

Konzentration: 1 mg/ml

Reinheit: > 95% (by SDS-PAGE).

Reinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Buffer: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.

Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Bilder

anti-Histone Deacetylase 1 (HDAC1) antibody

anti-Histone Deacetylase 1 (HDAC1) antibody (Image 2)