Matrix Metallopeptidase 1 (Interstitial Collagenase) (MMP1) Antikörper

Antigen: Matrix Metallopeptidase 1 (Interstitial Collagenase) (MMP1)

Synonyme: CLG, CLGN, Dm1-MMP, l(2)k04809, mmp1, DmelCG4859, CG4859, MMP1, Mmp1a, Mmp1

Klonalität: Polyklonal

Wirt: Kaninchen

Reaktivität: Human

Applikation: Western Blot (WB)

Produktnummer: ABIN457517

Produktbeschreibung

Produktmerkmale: 100 ug affinity purified rabbit anti-MMP-1 polyclonal antibody. Reacts with human. Reactivity to other species have not been determined. Recombinant human MMP-1 (Cat.# 7781-10) can be used as a positive control.

Weitere Bezeichnung: MMP-1

Immunogen: E. coli-expressed recombinant human MMP-1 (Cat.# 7781-10)

Format: Affinity-purified

Isotyp: IgG  (Passende Sekundärantikörper)

Beschreibung: Matrix metalloproteinases (MMPs) are zinc-dependent endopeptidases that degrade substances within the extracellular matrix. The MMP family includes six different groups of enzymes: collagenases, gelatinases, stromelysins, transmembrane MMPs, matrilysins and others. MMPs are secreted as proenzymes that have to be cleaved in order to be activated. Other MMPs, plasmins as well as other factors activate MMPs. MMPs are thought to play an important role in tissue remodeling associated with various physiological and pathological processes. MMP1 cleaves collagens of types I, II, III, VII and X.  MMP1 is thought to play an important role in rheumatoid and osteo-arthritis pathogenesis as mediators of cartilage and bone destruction.

Anwendungen

Applikationshinweise: Western blotting (0.5-4 µg/ml). However, the optimal conditions should be determined individually.

Konzentration: 0.5 mg/ml

Buffer: 100 µg (0.5 mg/ml) affinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal.

Lagerung: Store at -20°C. Shipped on gel packs. Shelf Life: 12 months.

Beschränkungen: Nur für Forschungszwecke einsetzbar