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Importin 11 Antikörper (N-Term)

IPO11 Reaktivität: Human WB, EIA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN453706
  • Target Alle Importin 11 (IPO11) Antikörper anzeigen
    Importin 11 (IPO11)
    Bindungsspezifität
    • 10
    • 9
    • 8
    • 7
    • 7
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reaktivität
    • 47
    • 6
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 47
    Kaninchen
    Klonalität
    • 46
    Polyklonal
    Konjugat
    • 23
    • 6
    • 5
    • 5
    • 4
    • 4
    Dieser Importin 11 Antikörper ist unkonjugiert
    Applikation
    • 41
    • 32
    • 6
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    Spezifität
    This antibody reacts to IPO11.
    Aufreinigung
    Affinity chromatography on Protein A
    Immunogen
    KLH conjugated synthetic peptide selected from the N-term region of human IPO11
    Top Product
    Discover our top product IPO11 Primärantikörper
  • Applikationshinweise
    ELISA: 1/1,000. Western blotting: 1/100 - 1/500.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.25 mg/mL
    Buffer
    PBS with 0.09 % (W/V) sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    Importin 11 (IPO11)
    Andere Bezeichnung
    RanBP11 / Importin-11 (IPO11 Produkte)
    Synonyme
    MGC83107 antikoerper, IPO11 antikoerper, slrn antikoerper, ranbp11 antikoerper, RanBP11 antikoerper, 1700081H05Rik antikoerper, 2510001A17Rik antikoerper, AI314624 antikoerper, AW555235 antikoerper, E330021B14Rik antikoerper, Ranbp11 antikoerper, importin 11 S homeolog antikoerper, importin 11 antikoerper, importin-11 antikoerper, ipo11.S antikoerper, ipo11 antikoerper, IPO11 antikoerper, AFUA_1G03590 antikoerper, BDBG_04626 antikoerper, LOC100162908 antikoerper, Ipo11 antikoerper
    Hintergrund
    IPO11 functions in nuclear protein import as nuclear transport receptor. It serves as receptor for nuclear localization signals (NLS) in cargo substrates and is thought to mediate docking of the importin/substrate complex to the nuclear pore complex (NPC) through binding to nucleoporin and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to the importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP-and GDP-bound forms of Ran between the cytoplasm and nucleus (By similarity). It mediates the nuclear import of UBE2E3, and of RPL12 (By similarity).Synonyms: IPO11, Imp11, Ran-binding protein 11
    Gen-ID
    51194
    NCBI Accession
    NP_057422
    UniProt
    Q9UI26
    Pathways
    Protein targeting to Nucleus
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