MYCN Antikörper (Mycn) (C-Term)

Details for Product anti-MYCN Antibody No. ABIN453206, Anbieter: Anmelden zum Anzeigen
Antigen
  • MODED
  • MYCNOT
  • N-myc
  • NMYC
  • ODED
  • bHLHe37
  • Nmuc1
  • Nmyc
  • Nmyc-1
  • Nmyc1
  • c-nmyc
  • olfactory receptor, family 8, subfamily S, member 1-like
  • v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
  • v-myc myelocytomatosis viral related oncogene, neuroblastoma derived
  • v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)
  • LOC515887
  • MYCN
  • Mycn
Epitop
C-Term
15
8
4
4
4
3
3
2
2
2
1
1
1
Reaktivität
Human
93
56
31
3
2
2
2
2
1
1
1
Wirt
Kaninchen
59
36
Klonalität
Polyklonal
Konjugat
Dieser MYCN Antikörper ist unkonjugiert
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Applikation
Enzyme Immunoassay (EIA), Western Blotting (WB)
71
21
18
17
16
13
5
4
3
3
3
3
2
1
1
1
Optionen
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Immunogen KLH conjugated synthetic peptide selected from the C-terminal region of human MYCN
Spezifität This antibody reacts to MYCN.
Reinigung Saturated Ammonium Sulfate (SAS) precipitation
Andere Bezeichnung MYCN (MYCN Antibody Abstract)
Hintergrund MYCN is a member of the MYC family and a protein with a basic helix-loop-helix (bHLH) domain. This protein is located in the nucleus and must dimerize with another bHLH protein in order to bind DNA. Amplification of its gene is associated with a variety of tumors, most notably neuroblastomas.Synonyms: Class E basic helix-loop-helix protein 37, N-myc proto-oncogene protein, NMYC
Gen-ID 4613
NCBI Accession NP_005369
UniProt P04198
Applikationshinweise ELISA: 1/1,000. Western blotting: 1/50 - 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 0.25 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freezing and thawing.
Lagerung 4 °C/-20 °C
Informationen zur Lagerung Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Bilder des Herstellers
Western Blotting (WB) image for anti-MYCN Antikörper (Mycn) (C-Term) (ABIN453206) Western blot analysis of MYCN antibody (C-term) in CEM cell line lysates (35ug/lane)....
Allgemeine Veröffentlichungen Alvarez-Rodríguez, Pons: "Expression of the proneural gene encoding Mash1 suppresses MYCN mitotic activity." in: Journal of cell science, Vol. 122, Issue Pt 5, pp. 595-9, 2009 (PubMed).

Combaret, Hogarty, London, McGrady, Iacono, Brejon, Swerts, Noguera, Gross, Rousseau, Puisieux: "Influence of neuroblastoma stage on serum-based detection of MYCN amplification." in: Pediatric blood & cancer, Vol. 53, Issue 3, pp. 329-31, 2009 (PubMed).