Hemochromatosis (HFE) (N-Term) Antikörper

Antigen: Hemochromatosis (HFE)

Synonyme: HH, HFE1, HLA-H, MVCD7, MGC103790, dJ221C16.10.1

Epitope: N-Term

Klonalität: Polyklonal

Wirt: Kaninchen

Reaktivität: Human

Applikation: Enzyme Immunoassay (EIA), Western Blot (WB)

Produktnummer: ABIN453092

Produktbeschreibung

Produktmerkmale: Synonyms: Hereditary hemochromatosis protein

Weitere Bezeichnung: HFE / HLAH

Gen-ID: 3077

Swiss-Prot: Q30201

Immunogen: KLH conjugated synthetic peptide selected from the N-terminal region of human HFE

Kreuzreaktivität: Human

Beschreibung: HFE is a membrane protein that is similar to MHC class I-type proteins and associates withbeta2-microglobulin (beta2M). It is thought that this protein functions to regulate ironabsorption by regulating the interaction of the transferrin receptor with transferrin. The ironstorage disorder, hereditary haemochromatosis, is a recessive genetic disorder that resultsfrom defects in its gene.

Spezifität: This antibody detects HFE at N-term. Species Reactivity: Tested: HumanAdd. Information: Molecular weight: 40108 Da

Anwendungen

Applikationshinweise: Western blot: 1: 50 - 1: 100. ELISA: 1: 1,000. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.

Konzentration: 0.25 mg/ml

Buffer: PBS with 0.09% (W/V) sodium azide

Lagerung: Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer. Avoidrepeated freezing and thawing. Shelf life: one year from despatch.

Beschränkungen: Nur für Forschungszwecke einsetzbar