Acyl-CoA Dehydrogenase, C-4 To C-12 Straight Chain (ACADM) (AA 196-225) Antikörper

Details zu Produkt Nr. ABIN452704, Anbieter: Anmelden zum Anzeigen
Antigen
  • ACAD1
  • MCAD
  • MCADH
  • AU018656
  • fb53e01
  • wu:fb53e01
  • zgc:111905
  • zgc:56101
  • zgc:76911
  • acyl-CoA dehydrogenase medium chain
  • acyl-CoA dehydrogenase, C-4 to C-12 straight chain L homeolog
  • acyl-Coenzyme A dehydrogenase, medium chain
  • acyl-CoA dehydrogenase, C-4 to C-12 straight chain
  • ACADM
  • acadm.L
  • Acadm
  • acadm
Epitop
AA 196-225
20
10
8
7
5
4
4
2
1
1
1
1
Reaktivität
Human, Maus
104
48
40
7
5
4
4
2
2
1
1
1
Wirt
Kaninchen
77
21
9
Klonalität
Polyklonal
Konjugat
Unkonjugiert
4
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Applikation
Enzyme Immunoassay (EIA), Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
86
33
33
26
15
13
10
5
3
1
Optionen
Hersteller
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Hersteller Produkt- Nr.
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Immunogen KLH conjugated synthetic peptide between 196~225 amino acids from the Center region of Human ACADM.
Isotyp Ig
Spezifität This antibody detects ACADM at Center.
Kreuzreaktivität (Details) Species reactivity (tested):Human, Mouse.
Reinigung Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS
Andere Bezeichnung ACADM (ACADM Antibody Abstract)
Hintergrund ACADM protein is a medium chain specific (C4 to C12 straight chain) acyl Coenzyme A dehydrogenase. The enzyme catalyzes the initial step of the mitochondrial fatty acid beta oxidation pathway. ACADM expression is induced during periods of fasting, when reliance on fatty acids for energy is increased. Clinical phenotypes are associated with ACADM hereditary deficiency.Synonyms: MCAD, Medium-chain specific acyl-CoA dehydrogenase mitochondrial
Molekulargewicht 46588 Da
Gen-ID 34
NCBI Accession NP_000007
UniProt P11310
Forschungsgebiet Cancer, Metabolism
Pathways Regulation of Lipid Metabolism by PPARalpha, Cellular Glucan Metabolic Process, Regulation of Carbohydrate Metabolic Process, Monocarboxylic Acid Catabolic Process
Applikationshinweise Western blot: 1: 50 - 1: 100. ELISA: 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 0.25 mg/mL
Buffer PBS with 0.09 % (W/V) Sodium Azide as preservative
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freezing and thawing.
Lagerung 4 °C/-20 °C
Informationen zur Lagerung Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Bilder des Herstellers
 image for anti-Acyl-CoA Dehydrogenase, C-4 To C-12 Straight Chain (ACADM) (AA 196-225) antibody (ABIN452704) anti-Acyl-CoA Dehydrogenase, C-4 To C-12 Straight Chain (ACADM) (AA 196-225) antibody
 image for anti-Acyl-CoA Dehydrogenase, C-4 To C-12 Straight Chain (ACADM) (AA 196-225) antibody (ABIN452704) anti-Acyl-CoA Dehydrogenase, C-4 To C-12 Straight Chain (ACADM) (AA 196-225) antibody (Image 2)
 image for anti-Acyl-CoA Dehydrogenase, C-4 To C-12 Straight Chain (ACADM) (AA 196-225) antibody (ABIN452704) anti-Acyl-CoA Dehydrogenase, C-4 To C-12 Straight Chain (ACADM) (AA 196-225) antibody (Image 3)
 image for anti-Acyl-CoA Dehydrogenase, C-4 To C-12 Straight Chain (ACADM) (AA 196-225) antibody (ABIN452704) anti-Acyl-CoA Dehydrogenase, C-4 To C-12 Straight Chain (ACADM) (AA 196-225) antibody (Image 4)
Allgemeine Veröffentlichungen Ferreira, Orlandi, Oliveira, Malta, Caxito, Gomes, Valadares, Godard: "A985G mutation incidence in the medium-chain acyl-CoA dehydrogenase (MCAD) gene in Brazil." in: Genetics and molecular research : GMR, Vol. 8, Issue 2, pp. 487-93, 2009 (PubMed).

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