In den Warenkorb
Bestellen Sie auch über:
+49 (0)241 95 163 153
+49 (0)241 95 163 155

Calcitonin-Related Polypeptide alpha (CALCA) Antikörper

Antigen

Calcitonin-Related Polypeptide alpha (CALCA)

Synonyme CALCA, CALC3, MGC152154, CT, KC, CGRP, CALC1, CGRP1, CGRP-I, MGC126648, CFP1, CGBP, SPP1, PCCX1, PHF18, hCGBP, HsT2645, 2410002I16Rik, 5830420C16Rik, CALC, calcitonin, calca, ci-ct
Klonalität Polyklonal
Wirt
Alternativen

Kaninchen

Reaktivität
Alternativen

Human

Applikation
Alternativen Immunhistochemie (Gefrierschnitte) (IHC (fro)), Immunhistochemie (Paraffinschnitte) (IHC (p))
Produktnummer ABIN452432
Menge 50 µl  (Varianten)
Preis 330,00 €   Zzgl. Versandkosten €20,00 und MWSt
Lieferung nach
Verfügbarkeit Lieferung in 7 bis 10 Werktagen

Produktbeschreibung

Produktmerkmale Synonyms: CALCA, CALC1
Weitere Bezeichnung Calcitonin
Gen-ID 796
Swiss-Prot P01258
Immunogen Synthetic human calcitonin (Ciba Geigy), conjugated to KLH
Kreuzreaktivität Human, Ratte (Rattus)
Isotyp IgG  (Passende Sekundärantikörper)
Beschreibung Calcitonin is a 32 amino acid peptide hormone synthesized by the parafollicular cells ofthe thyroid. It causes a rapid, but short lived, reduction in serum calcium and phosphateby promoting the incorporation of those ions in the bones. This effect is opposite to that ofparathyroid hormone. Staining for calcitonin may be used for the identification of aspectrum of C cell proliferative abnormalities ranging from C cell hyperplasia to invasivetumors. Staining for calcitonin in medullary carcinoma of the thyroid produces a finegranular pattern in the cytoplasm. Amyloid deposits within the tumor may also exhibitvarying degrees of calcitonin activity.
Spezifität Histochemical demonstration of calcitonin is important in the diagnosis of medullarycarcinoma of the thyroid and of C-cell hyperplasia. It may also occur in bronchialcarcinoids, in tumors of adrenal medulla and of pancreatic islets. Absorption with 10-100µg calcitonin per ml diluted antiserum abolishes the staining. A cytoplasmic staining isobserved. Species: Human, Rat. Others not tested.

Anwendungen

Applikationshinweise Immunohistochemistry on frozen and paraffin sections: 1/500 – 1/800 using PAP, withovernight incubation at 2-8°COther applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Reinigung Serum
Lagerung Prior to reconstitution store at 2-8°C. Following reconstitution store the antibody at -20°C. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Forschungsgebiet Krebs, Wachstumsfaktoren, Hormone, Zytoskelett, Mikrofilamente, Angeborene Immunität, Chemokine
Beschränkungen Nur für Forschungszwecke einsetzbar

Alternativen

Alternativen zu Antigen "Calcitonin-Related Polypeptide alpha (CALCA)", Typ "Antikörper" finden
Wirte Kaninchen (106), Maus (43), Ziege (7), Schaf (6), Huhn (4), Meerschweinchen (2)
Reaktivitäten Human (140), Ratte (Rattus) (41), Hund (27), Maus (21), Schwein (10), Kaninchen (10), Schaf (10), Hamster (7), Affe (7), Säugetiere (4), Rind (Kuh) (3), Pferd (2), Huhn (1), Fisch (1), Meerschweinchen (1), Reptile (1), Zebrafisch (Danio rerio) (1)
Applikationen Immunfluoreszenz (IF) (50), Enzyme Immunoassay (EIA) (44), Immunhistochemie (Paraffinschnitte) (IHC (p)) (43), Western Blot (WB) (37), Durchflusszytometrie (FACS) (36), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (30), Radioimmunoassay (RIA) (22), ELISA (13), Immunhistochemie (IHC) (11), Immunpräzipitation (IP) (5), Immunhistochemie (formalinfixierte Schnitte) (IHC (f)) (4), Electrophoresis (EP) (3), Dot Blot (Dot) (2), ELISA (Fangantikörper) (2), ELISA (Detektionsantikörper) (2), Immunoelectron Microscopy (IEM) (2), Immunzytochemie (ICC) (1), Neutralisierung (Neut) (1)
Konjugate Biotin (6), Alexa Flour 488 (2), Alexa Fluor 350 (2), Alexa Fluor 488 (2), Alexa Fluor 555 (2), Alexa Fluor 647 (2), Cy3 (2), Cy5 (2), Cy5.5 (2), Cy7 (2), FITC (2), Gold (2), HRP (2), PE (2), PE,Cy3 (2), PE,Cy5 (2), PE,Cy5.5 (2), PE,Cy7 (2), RBITC (2)
Epitope AA 1-32 (8), C-Term (3)