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FMR1 Antikörper (Internal Region)

FMR1 Reaktivität: Human, Ratte WB, EIA Wirt: Ziege Polyclonal unconjugated
Produktnummer ABIN452426
  • Target Alle FMR1 Antikörper anzeigen
    FMR1 (Fragile X Mental Retardation 1 (FMR1))
    Bindungsspezifität
    • 15
    • 10
    • 8
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 116-130, Internal Region
    Reaktivität
    • 70
    • 47
    • 36
    • 15
    • 6
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Ratte
    Wirt
    • 58
    • 15
    • 2
    Ziege
    Klonalität
    • 51
    • 24
    Polyklonal
    Konjugat
    • 44
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser FMR1 Antikörper ist unkonjugiert
    Applikation
    • 68
    • 29
    • 18
    • 15
    • 14
    • 14
    • 10
    • 7
    • 5
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    Sequenz
    c-NPNKPATKDT FHKIK
    Spezifität
    This antibody Recognizes FMR1.
    Kreuzreaktivität (Details)
    Species reactivity (expected):Rat.
    Species reactivity (tested):Human.
    Aufreinigung
    Ammonium Sulphate Precipitation followed by antigen Affinity Chromatography using the immunizing peptide.
    Immunogen
    Peptide with sequence from the internal region of the protein sequence according to NP_002015.1. Genename: FMR1
    Top Product
    Discover our top product FMR1 Primärantikörper
  • Applikationshinweise
    Peptide ELISA: 1/32000. Western blot: Approx 70Da band observed in lysates of cell lines HeLa and Jurkat(calculated MW of 71.2 kDa according to NP_002015.1). Recommended concentration: 0.3 -1 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    0.5 mg/mL
    Buffer
    Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • Target
    FMR1 (Fragile X Mental Retardation 1 (FMR1))
    Andere Bezeichnung
    FMR1 / FMRP (FMR1 Produkte)
    Synonyme
    AT24755 antikoerper, BcDNA:GM08679 antikoerper, CG6203 antikoerper, Dmel\\CG6203 antikoerper, EP(3)3517 antikoerper, FMR antikoerper, FMR1 antikoerper, FMRP antikoerper, FMRp antikoerper, FXR antikoerper, Fmrp antikoerper, cg6203 antikoerper, dFMR antikoerper, dFMR1 antikoerper, dFMRP antikoerper, dFXR antikoerper, dFXR1 antikoerper, dFXRP antikoerper, dFmr1 antikoerper, dFmrp antikoerper, dfmr antikoerper, dfmr1 antikoerper, dfxr antikoerper, dfxr1 antikoerper, dmfr1 antikoerper, fmr antikoerper, fmr1 antikoerper, FRAXA antikoerper, POF antikoerper, POF1 antikoerper, zFMR1 antikoerper, Fmr-1 antikoerper, CG6203 gene product from transcript CG6203-RC antikoerper, fragile X mental retardation 1 antikoerper, fragile X mental retardation syndrome 1 antikoerper, Fmr1 antikoerper, FMR1 antikoerper, fmr1 antikoerper
    Hintergrund
    FMRP is a RNA-binding protein that is associated to polysomes and may be involved in the transport of mRNA from the nucleus to the cytoplasm. Defects in FMR1 are the cause of Fragile X syndrome, which is a common genetic disease characterized by moderate to severe mental retardation, macroorchidism, large ears, prominent jaw, and high-pitched, jocular speech. The defect in most fragile X syndrome patients results from an amplification of a CGG repeat region which is directly in front of the coding region.Synonyms: Fragile X mental retardation 1 protein, Protein FMR-1
    Gen-ID
    2332
    NCBI Accession
    NP_002015
    UniProt
    Q06787
    Pathways
    Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
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