TMEM173 Antikörper (Transmembrane Protein 173)

Details for Product anti-TMEM173 Antibody No. ABIN4356573, Anbieter: Anmelden zum Anzeigen
Antigen
  • ERIS
  • MITA
  • MPYS
  • NET23
  • STING
  • 2610307O08Rik
  • Mita
  • RGD1562552
  • transmembrane protein 173
  • TMEM173
  • Tmem173
Alternativen
anti-Ratte (Rattus) TMEM173 Antikörper für ELISA
Reaktivität
Human, Maus, Primate, Ratte (Rattus)
135
39
28
2
1
1
1
1
1
1
1
Wirt
Kaninchen
96
46
Klonalität
Polyklonal
Konjugat
Dieser TMEM173 Antikörper ist unkonjugiert
6
6
3
3
3
3
3
3
2
2
2
2
2
1
1
1
1
1
1
1
Applikation
Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
97
51
48
40
19
14
13
12
10
7
4
4
1
Optionen
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Immunogen A portion of amino acids 310-360 of human STING was used as the immunogen.
Reinigung Protein A purified
Andere Bezeichnung STING/TMEM173 (TMEM173 Antibody Abstract)
Hintergrund Gene Symbol: TMEM173
Gen-ID 340061
UniProt Q86WV6
Pathways Activation of Innate immune Response
Applikationshinweise Western Blot 1:500-1:1000, Immunohistochemistry 1:200-1:400, Immunocytochemistry/Immunofluorescence 1:200, Immunohistochemistry-Paraffin 1:200-1:400, Immunofluorescence 1:200, Immunocytochemistry 1:200
Kommentare

The antibodies are intended for use in vitro experiments only. Our antibodies have not been tested nor are recommended for use in vivo.

Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 1.0 mg/mL
Buffer PBS
Buffer contains: 0.05 % Sodium Azide
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung 4 °C,-20 °C
Informationen zur Lagerung Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Bilder des Herstellers
Western Blotting (WB) image for anti-TMEM173 Antikörper (Transmembrane Protein 173) (ABIN4356573) Western Blot: STING/TMEM173 Antibody - Total protein from THP-1, HT-29, U2OS cells a...
Produkt verwendet in: Bhattacharya, Srinivasan, Abdisalaam, Su, Raj, Dozmorov, Mishra, Wakeland, Ghose, Mukherjee, Asaithamby: "RAD51 interconnects between DNA replication, DNA repair and immunity." in: Nucleic acids research, Vol. 45, Issue 8, pp. 4590-4605, 2017 (PubMed). Von den Autoren verwendete Methode: Immunohistochemistry (IHC) (Probematerial (Species): Human).

Li, Cheng, Yuan, Xu, Shu, Zhang, Xu, Tan, Rui, Li, Tan: "Antitumor Activity of cGAMP via Stimulation of cGAS-cGAMP-STING-IRF3 Mediated Innate Immune Response." in: Scientific reports, Vol. 6, pp. 19049, 2016 (PubMed). (Probematerial (Species): Mouse (Murine)). Weitere Details: Immunohistochemistry (Paraffin-embedded Sections)

Reinert, Lopušná, Winther, Sun, Thomsen, Nandakumar, Mogensen, Meyer, Vægter, Nyengaard, Fitzgerald, Paludan: "Sensing of HSV-1 by the cGAS-STING pathway in microglia orchestrates antiviral defence in the CNS." in: Nature communications, Vol. 7, pp. 13348, 2016 (PubMed). (Probematerial (Species): Fruit Fly (Drosophila sp.)).

Sun, Schattgen, Pisitkun, Jorgensen, Hilterbrand, Wang, West, Hansen, Horan, Jakobsen, OHare, Adler, Sun, Ploegh, Damania, Upton, Fitzgerald, Paludan: "Evasion of innate cytosolic DNA sensing by a gammaherpesvirus facilitates establishment of latent infection." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 194, Issue 4, pp. 1819-31, 2015 (PubMed). (Probematerial (Species): Human). Weitere Details: Immunocytochemistry,Immunofluorescence

Olagnier, Scholte, Chiang, Albulescu, Nichols, He, Lin, Snijder, van Hemert, Hiscott: "Inhibition of dengue and chikungunya virus infections by RIG-I-mediated type I interferon-independent stimulation of the innate antiviral response." in: Journal of virology, Vol. 88, Issue 8, pp. 4180-94, 2014 (PubMed). (Probematerial (Species): Human). Weitere Details: Western Blotting

Chiliveru, Rahbek, Jensen, Jørgensen, Nissen, Christiansen, Mogensen, Jakobsen, Iversen, Johansen, Paludan: "Inflammatory cytokines break down intrinsic immunological tolerance of human primary keratinocytes to cytosolic DNA." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 192, Issue 5, pp. 2395-404, 2014 (PubMed). (Probematerial (Species): Human). Weitere Details: Immunocytochemistry,Immunofluorescence

Panchanathan, Liu, Xin, Choubey: "Identification of a negative feedback loop between cyclic di-GMP-induced levels of IFI16 and p202 cytosolic DNA sensors and STING." in: Innate immunity, Vol. 20, Issue 7, pp. 751-9, 2014 (PubMed). (Probematerial (Species): Mouse (Murine)). Weitere Details: Western Blotting

Hansen, Prabakaran, Laustsen, Jørgensen, Rahbæk, Jensen, Nielsen, Leber, Decker, Horan, Jakobsen, Paludan: "Listeria monocytogenes induces IFNβ expression through an IFI16-, cGAS- and STING-dependent pathway." in: The EMBO journal, Vol. 33, Issue 15, pp. 1654-66, 2014 (PubMed). (Probematerial (Species): Human). Weitere Details: Immunocytochemistry,Immunofluorescence

Horan, Hansen, Jakobsen, Holm, Søby, Unterholzner, Thompson, West, Iversen, Rasmussen, Ellermann-Eriksen, Kurt-Jones, Landolfo, Damania, Melchjorsen, Bowie, Fitzgerald, Paludan: "Proteasomal degradation of herpes simplex virus capsids in macrophages releases DNA to the cytosol for recognition by DNA sensors." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 190, Issue 5, pp. 2311-9, 2013 (PubMed).

Jakobsen, Bak, Andersen, Berg, Jensen, Tengchuan, Jin, Laustsen, Hansen, Ostergaard, Fitzgerald, Xiao, Mikkelsen, Mogensen, Paludan: "IFI16 senses DNA forms of the lentiviral replication cycle and controls HIV-1 replication." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 110, Issue 48, pp. E4571-80, 2013 (PubMed). (Probematerial (Species): Human). Weitere Details: Immunocytochemistry,Immunofluorescence

Orzalli, DeLuca, Knipe: "Nuclear IFI16 induction of IRF-3 signaling during herpesviral infection and degradation of IFI16 by the viral ICP0 protein." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 109, Issue 44, pp. E3008-17, 2012 (PubMed). (Probematerial (Species): Human). Weitere Details: Immunocytochemistry,Western Blotting,Immunofluorescence

Furr, Chauhan, Moerdyk-Schauwecker, Marriott: "A role for DNA-dependent activator of interferon regulatory factor in the recognition of herpes simplex virus type 1 by glial cells." in: Journal of neuroinflammation, Vol. 8, pp. 99, 2011 (PubMed). (Probematerial (Species): Mouse (Murine)). Weitere Details: Western Blotting