CD8 Antikörper (CD8a Molecule) (PE)

Details for Product anti-CD8A Antibody No. ABIN4262056, Anbieter: Anmelden zum Anzeigen
Antigen
  • cd8
  • LOC100136450
  • BB154331
  • Ly-2
  • Ly-35
  • Ly-B
  • Lyt-2
  • zgc:136643
  • CD8
  • Leu2
  • MAL
  • p32
  • RHACD8-4
  • CD8 antigen, alpha chain
  • CD8 antigen, alpha polypeptide
  • CD8 alpha
  • T-cell surface glycoprotein CD8 alpha chain-like
  • CD8a molecule
  • Cd8a
  • cd8
  • LOC100136450
  • LOC100387674
  • cd8a
  • CD8A
Reaktivität
Maus, Ratte (Rattus)
600
495
126
92
44
26
19
13
13
13
12
12
9
5
5
5
4
4
4
2
2
1
1
Wirt
Ratte
764
458
198
1
1
Klonalität (Klon)
Monoklonal ()
Konjugat
Dieser CD8 Antikörper ist konjugiert mit PE
150
142
91
55
45
36
36
33
29
27
24
23
23
23
23
22
20
19
19
18
14
13
11
11
11
10
9
7
7
7
5
4
4
4
4
4
4
4
3
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Applikation
Flow Cytometry (FACS)
1149
446
365
256
246
236
198
185
174
35
34
20
16
13
11
11
9
7
6
6
6
3
2
2
2
2
2
2
1
1
1
1
1
1
1
Optionen
Hersteller
Anmelden zum Anzeigen
Hersteller Produkt- Nr.
Anmelden zum Anzeigen
Immunogen Mouse thymus or spleen.
Klon 53-6-7
Isotyp IgG2a kappa
Reinigung Protein A or G purified
Andere Bezeichnung CD8 alpha (CD8A Antibody Abstract)
Hintergrund Gene Symbol: CD8A
Molekulargewicht Theoretical MW: 27 kDa
Gen-ID 925
Pathways T-Zell Rezeptor Signalweg
Applikationshinweise Each lot of this CD8a antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is <0.25 μg/10^6 cells in 100 μL volume. It is recommended that the reagent be titrated for optimal performance for each application. The 53-6.7 antibody has been reported to block antigen presentation via MHC class I and inhibit T cell responses to IL-2. This antibody has also been used for depletion of CD8a+ cells. Additional reported applications (for the relevant formats) include: immunoprecipitation, in vivo and in vitro cell depletion, inhibition of CD8 T cell proliferation, blocking of cytotoxicity, and immunohistochemical staining of both acetone-fixed frozen sections and zinc-fixed paraffin-embedded sections. This antibody is not recommended for immunohistochemistry of formalin-fixed paraffin sections. Immunocytochemistry/Immunofluorescence was reported in scientific literature. Use in Immunohistochemistry-Paraffin reported in scientific literature (PMID 24565643)
Kommentare

The antibodies are intended for use in vitro experiments only. Our antibodies have not been tested nor are recommended for use in vivo.

Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Buffer PBS
Buffer contains: 0.05 % Sodium Azide
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung 4 °C
Informationen zur Lagerung Store at 4°C in the dark.
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