TGF-beta Receptor II Antikörper

Antigen: TGF-beta Receptor II

Klonalität: Polyklonal

Wirt: Kaninchen

Reaktivität: Human, Maus, Ratte (Rattus)

Applikation: Western Blot (WB)

Produktnummer: ABIN411603

Produktbeschreibung

Produktmerkmale: 100 ug affinity purified rabbit anti-human TGF-beta Receptor II polyclonal antibody. Tested in Western blot analysis.

Gen-ID: 81810

Immunogen: Synthetic peptide surrounding amino acid 555 of rat TGF-β Receptor II.

Isotyp: IgG  (Passende Sekundärantikörper)

Beschreibung: TGF-β (Transforming growth factor-beta superfamily members are critical regulators of cell proliferation, differentiation, morphogenesis, and pathogenesis. TGF-beta receptor is a serine/threonine kinase receptor complex that consists of two distinct transmembrane proteins known as type I and type II receptors. In response to ligand binding, the type II receptors form a stable complex with the type I receptors allowing phosphorylation and thus activation of the type I receptor kinases.

Anwendungen

Applikationshinweise: The antibody can be used for Western blotting (0.5-4 µg/ml). However, the optimal conditions should be determined individually. Blocking peptide (Cat.# 5639RBP-50) is available separately.

Konzentration: 0.5 mg/ml

Reinigung: Affinity Purified Antibody

Buffer: 100 µg (0.5 mg/ml) affinity purified rabbit polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal.

Lagerung: Store at -20°C. Shelf life: 12 months. The antibody solution should be gently mixed before use.

Forschungsgebiet: Wachstumsfaktoren, Signaltransduktion, Rezeptoren

Beschränkungen: Nur für Forschungszwecke einsetzbar