Notch 1 (NOTCH1) Antikörper
| Antigen |
|
| Synonyme |
hN1, TAN1, Mis6, Tan1, lin-12, 9930111A19Rik, NOTCH, NOTCH1, notch1, hn1, tan1, notch, xotch, xnotch, notch-1, xnotch1 |
| Klonalität |
Polyklonal |
|
Wirt
|
|
|
Reaktivität
|
|
|
Applikation
|
Durchflusszytometrie (FACS) (46), Western Blot (WB) (46), Immunhistochemie (Paraffinschnitte) (IHC (p)) (21), Immunhistochemie (IHC) (14), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (13), ELISA (10), Enzyme Immunoassay (EIA) (10), Intrazelluläre Durchflusszytometrie (ICFC) (6), Immunpräzipitation (IP) (5), Immunfluoreszenz (IF) (4), Immunzytochemie (ICC) (3), Dot Blot (Dot) (2), Funktionale Studien (Func) (2)
|
| Produktnummer |
ABIN411548 |
| Menge |
100 µg (0.5 mg/ml) |
| Preis |
258,88 € Zzgl. Versandkosten €20,00 und MWSt
|
| Lieferung nach |
|
| Verfügbarkeit |
Lieferung in 7 bis 10 Werktagen |
|
Produktmerkmale
|
100 ug affinity purified rabbit anti-Notch 1 polyclonal antibody. Reacts with human/mouse/rat. Tested in Western Blot. Other applications have not been determined.
|
|
Weitere Bezeichnung
|
Notch 1
|
|
Gen-ID
|
18128
|
|
Immunogen
|
Synthetic peptide corresponding to residues surrounding amino acid 1760 of mouse Notch1
|
|
Isotyp
|
IgG (Passende Sekundärantikörper)
|
|
Beschreibung
|
Notch proteins are transmembrane receptor that regluate cell fate decisions. Four Notch homologs have been identified in mammals namely Notch 1, Notch 2, Notch 3 and Notch 4. The membrane ligand for Notch includes Jagged 1, Jagged 2 and Delta. Notch 1 is a 270 kDa transmembrane receptor that can be activated by Delta (Dl) ligand. Activation of Notch 1 will result in the proteolytic cleavage of Notch 1 into a 120 kDa length protein.
|
|
Spezifität
|
The antibody recognizes a 120 kDa band from samples of human and mouse origins. Reactivity to other species has not been tested.
|
|
Applikationshinweise
|
Western blotting (0.5-4 µg/ml). However, the optimal concentrations should be determined individually. The antibody recognizes a 120 kDa band from samples of human and mouse origins. Reactivity to other species has not been tested.
|
|
Konzentration
|
0.5 mg/ml
|
|
Reinigung
|
Affinity Purified Antibody
|
|
Buffer
|
100 µg (0.5mg/ml) affinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA and 0.01% thimerosal.
|
|
Lagerung
|
Store at -20°C. Shelf life: 12 months. The antibody solution should be gently mixed before use.
|
|
Beschränkungen
|
Nur für Forschungszwecke einsetzbar
|
Alternativen zu Antigen "Notch 1 (NOTCH1)", Typ "Antikörper" finden
|
Wirte
|
Maus (53), Kaninchen (37), Hamster (10), Ziege (4)
|
|
Reaktivitäten
|
Human (70), Maus (65), Ratte (Rattus) (14), Zebrafisch (Danio rerio) (2), Huhn (1)
|
|
Applikationen
|
Durchflusszytometrie (FACS) (46), Western Blot (WB) (46), Immunhistochemie (Paraffinschnitte) (IHC (p)) (21), Immunhistochemie (IHC) (14), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (13), ELISA (10), Enzyme Immunoassay (EIA) (10), Intrazelluläre Durchflusszytometrie (ICFC) (6), Immunpräzipitation (IP) (5), Immunfluoreszenz (IF) (4), Immunzytochemie (ICC) (3), Dot Blot (Dot) (2), Funktionale Studien (Func) (2)
|
|
Konjugate
|
PE (11), Biotin (6), Alexa Fluor 647 (2), RPE (1)
|
|
Epitope
|
C-Term (5), Cleaved N-Term (1), Cleaved-Val1744 (1), Cleaved-Val1754 (1), Intra (1), N-Term (1), internal (1)
|