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Antikörper
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anti-Matrix Metallopeptidase 11 (Stromelysin 3) (MMP11) Antikörper
Matrix Metallopeptidase 11 (Stromelysin 3) (MMP11) Antikörper
| Antigen |
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| Synonyme |
ST3, SL-3, STMY3 |
| Klonalität |
Polyklonal |
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Wirt
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Reaktivität
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Applikation
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Western Blot (WB) (34), Immunfluoreszenz (IF) (23), Durchflusszytometrie (FACS) (18), Immunhistochemie (Paraffinschnitte) (IHC (p)) (18), Immunpräzipitation (IP) (16), Enzyme Immunoassay (EIA) (7), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (6), Immunhistochemie (IHC) (4), ELISA (3), Immunhistochemie (formalinfixierte Schnitte) (IHC (f)) (2), Dot Blot (Dot) (1), Immunzytochemie (ICC) (1), Immunoelectron Microscopy (IEM) (1)
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| Produktnummer |
ABIN411537 |
| Menge |
100 µg (0.5 mg/ml) |
| Preis |
258,88 € Zzgl. Versandkosten €20,00 und MWSt
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| Lieferung nach |
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| Verfügbarkeit |
Lieferung in 7 bis 10 Werktagen |
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Produktmerkmale
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100 ug affinity purified rabbit anti-MMP-11 polyclonal antibody. Reacts with human/mouse/rat. Detects the latent form (~68 kDa) and the activated forms (~55 kDa and ~40 kDa) of MMP-11 in Western blot analysis. Other applications have not been determined. Blocking peptide (Cat.# 3531RBP-50) is available separately.
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Weitere Bezeichnung
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MMP-11
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Gen-ID
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17385
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Immunogen
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Synthetic peptide surrounding amino acid 464 of mouse MMP-11
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Isotyp
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IgG (Passende Sekundärantikörper)
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Beschreibung
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The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including collagen, gelatin, fibronectin, laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester, lipopolysaccharide (LPS) or staphylococcal enterotoxin B (SEB). MMP catalysis requires both calcium and zinc. MMP-11 is specifically expressed in stromal cells of breast carcinomas and contributes to epithelial cell malignancies.
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Spezifität
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The antibody recognizes the latent form (~68 kDa) and the active forms (~55 kDa and ~40 kDa) of MMP-11 from human, mouse, and rat origins.
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Applikationshinweise
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Western blotting (0.5-4 µg/ml). However, the optimal conditions should be determined individually. Blocking peptide (3531RBP-50) is available separately. The antibody recognizes the latent form (~68 kDa) and the active forms (~55 kDa and ~40 kDa) of MMP-11 from human, mouse, and rat origins.
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Konzentration
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0.5 mg/ml
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Reinigung
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Affinity Purified Antibody
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Buffer
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100 µg (0.5 mg/ml) immunoaffinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal.
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Lagerung
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Store at -20°C. Shelf life: 12 months. The antibody solution should be gently mixed before use.
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Beschränkungen
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Nur für Forschungszwecke einsetzbar
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Alternativen zu Antigen "Matrix Metallopeptidase 11 (Stromelysin 3) (MMP11)", Typ "Antikörper" finden
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Wirte
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Kaninchen (40), Maus (17)
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Reaktivitäten
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Human (55), Ratte (Rattus) (30), Maus (29), Rind (Kuh) (17), Hund (17), Schwein (16), Huhn (1), Pferd (1)
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Applikationen
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Western Blot (WB) (34), Immunfluoreszenz (IF) (23), Durchflusszytometrie (FACS) (18), Immunhistochemie (Paraffinschnitte) (IHC (p)) (18), Immunpräzipitation (IP) (16), Enzyme Immunoassay (EIA) (7), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (6), Immunhistochemie (IHC) (4), ELISA (3), Immunhistochemie (formalinfixierte Schnitte) (IHC (f)) (2), Dot Blot (Dot) (1), Immunzytochemie (ICC) (1), Immunoelectron Microscopy (IEM) (1)
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Konjugate
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Biotin (4), Alexa Flour 488 (1), Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1), RBITC (1)
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Epitope
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C-Term (3), N-Term (1)
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Alternativen 
