Mitofusin 2 (MFN2) Antikörper

Antigen: Mitofusin 2 (MFN2)

Synonyme: HSG, MARF, CMT2A, CPRP1, CMT2A2, KIAA0214, Fzo, D630023P19Rik, MGC81251, MFN2, hsg, marf, cmt2a, cprp1, cmt2a2, DKFZp459G151

Klonalität: Polyklonal

Wirt: Kaninchen

Reaktivität: Human, Maus, Ratte (Rattus)

Applikation: Western Blot (WB)

Produktnummer: ABIN411536

Produktbeschreibung

Produktmerkmale: 100 ug affinity purified rabbit anti-Mitofusin 2 polyclonal antibody. Reacts with human/mouse/rat. Tested in Western Blot. Other applications have not been determined.

Weitere Bezeichnung: Mitofusin 2

Gen-ID: 9927

Immunogen: Synthetic peptide corresponding to residues surrounding amino acid 719 of human Mitofusin 2

Isotyp: IgG  (Passende Sekundärantikörper)

Beschreibung: Mitofusin 2 (Mfn 2) is mostly expressed in the heart and muscle tissues. It is a transmembrane protein that mediates mitochondria fusion and plays a central role in the maintenance of mitochondrial morphology. A GTPase domain is required for the function of Mitofusin proteins. Mutations in Mfn2 can lead to Charcot-Marie-Tooth disease, a common inherited disorder of the peripheral nervous system. Mfn2 may also be associated with obesity and/or apoptosis.

Anwendungen

Applikationshinweise: Western blotting (0.5-4 µg/ml). However, the optimal concentrations should be determined individually. The antibody recognizes 68 kDa and 86 kDa bands from samples of human, mouse, rat origins. Reactivity to other species has not been tested.

Konzentration: 0.5 mg/ml

Reinigung: Affinity Purified Antibody

Buffer: 100 µg (0.5mg/ml) affinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA and 0.01% thimerosal.

Lagerung: Store at -20°C. Shelf life: 12 months. The antibody solution should be gently mixed before use.

Forschungsgebiet: Neurologie, Metabolismus, Apoptose/Nekrose, Organelle

Beschränkungen: Nur für Forschungszwecke einsetzbar