Suppressor of Tumorigenicity 14 Protein (ST14) Antikörper

Antigen: Suppressor of Tumorigenicity 14 Protein (ST14)

Synonyme: HAI, MTSP1, SNC19, MT-SP1, PRSS14, TADG15

Klonalität: Polyklonal

Wirt: Kaninchen

Reaktivität: Human, Maus, Ratte (Rattus)

Applikation: Western Blot (WB)

Produktnummer: ABIN411532

Produktbeschreibung

Produktmerkmale: 100 ug affinity purified rabbit anti-Matriptase polyclonal antibody. Reacts with human/mouse/rat. Tested in Western blot. Other applications have not been determined. Blocking peptide (Cat.# 3855BP-50) is available separately.

Weitere Bezeichnung: Matriptase

Gen-ID: 114093

Immunogen: Synthetic peptide surrounding amino acid 629 of rat Matriptase

Isotyp: IgG

Beschreibung: Matriptase or MT-SP1 is an epithelial-derived type II transmembrane serine protease that is highly expressd in human cancer-derived cell lines. Matriptase cleaves and activates protease activated receptor-2, pro-urokinase plasminogen activator and pro-hepatocyte growth factor. Matriptase is strongly inhibited by the hepatocyte growth factor activator inhibitor type 1 (HAI-1), which is a reactive site loop of Kunitz domain and also a transmembrane serine protease inhibitor.

Anwendungen

Applikationshinweise: Western blotting (0.5-4 µg/ml). However, the optimal concentrations should be determined individually. The antibody recognizes ~75 kDa doublets of Matriptase in samples from human, mouse and rat, origins. Reactivity to other species has not been tested.

Konzentration: 0.5 mg/ml

Reinigung: Affinity Purified Antibody

Buffer: 100 µg (0.5 mg/ml) affinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal.

Lagerung: Store at -20°C. Shelf life: 12 months. The antibody solution should be gently mixed before use.

Beschränkungen: Nur für Forschungszwecke einsetzbar