Insulin (INS) Antikörper

Antigen: Insulin (INS)

Synonyme: ILPR, IRDN, INS, MGC159719, ins1, xins, ins1-a, Insulin

Klonalität: Polyklonal

Wirt: Kaninchen

Reaktivität: Human

Applikation: Western Blot (WB)

Produktnummer: ABIN411521

Produktbeschreibung

Produktmerkmale: 100 ug affinity purified rabbit anti-human Insulin polyclonal antibody. Perform well in Western blot. Other applications have not been determined.

Weitere Bezeichnung: Insulin

Gen-ID: 3630

Immunogen: E. coli expressed recombinant human Insulin

Isotyp: IgG  (Passende Sekundärantikörper)

Beschreibung: Insulin is important in stimulating the uptake of glucose from blood in the skeletal muscle and adipose tissue. It is secrered by pancreatic β cells through a glucose sensing pathway. Insulin also increases cell permeability to monosaccharides, amino acids and fatty acids. Insulin is first formed as a precursor molecule, preproinsulin which is then processed into proinsulin and finally to the mature insulin hormone. A mature form of insulin has an A chain and a B chain that are connnected by two dilsufide bonds. Defects in insulin are the cause of type-II diabetes mellitus.

Spezifität: The antibody recognizes ~6 kDa Insulin in samples from human origins. Reactivity to other species has not been tested.

Anwendungen

Applikationshinweise: Western blotting (0.5-4 µg/ml). However, the optimal concentrations should be determined individually.

Konzentration: 0.5 mg/ml

Reinigung: Affinity Purified Antibody

Buffer: 100 µg (0.5 mg/ml) affinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal.

Lagerung: Store at -20°C. Shelf life: 12 months. The antibody solution should be gently mixed before use.

Forschungsgebiet: Neurologie, Diabetes, Hormone

Beschränkungen: Nur für Forschungszwecke einsetzbar