Hepatocyte Nuclear Factor 4 alpha (HNF4A) Antikörper

Antigen: Hepatocyte Nuclear Factor 4 alpha (HNF4A)

Synonyme: TCF, HNF4, MODY, MODY1, NR2A1, TCF14, HNF4a7, HNF4a8, HNF4a9, NR2A21, FLJ39654, HNF4alpha, HNF4A

Klonalität: Polyklonal

Wirt: Kaninchen

Reaktivität: Human

Applikation: ELISA, Western Blot (WB)

Produktnummer: ABIN411506

Produktbeschreibung

Produktmerkmale: 100 µg (0.25 mg/ml) affinity purified antibody. Reacts with human. Tested in ELISA and Western Blot.

Weitere Bezeichnung: HNF4A

Gen-ID: 3172

Immunogen: Synthetic peptide selected from the center region of human HNF4A

Isotyp: IgG  (Passende Sekundärantikörper)

Beschreibung: HNF4A is a nuclear transcription factor which binds DNA as a homodimer. This protein controls the expression of several genes, including hepatocyte nuclear factor 1 alpha, a transcription factor which regulates the expression of several hepatic genes. This protein may play a role in development of the liver, kidney, and intestines. Mutations in the HNF4A gene have been associated with monogenic autosomal dominant non-insulin-dependent diabetes mellitus type I.

Spezifität: The antibody detects a ~ 53 kDa band, corresponding to the expected molecular mass of HNF4 on immunoblots.

Anwendungen

Applikationshinweise: The antibody can be used for ELISA (0.25 µg/ml) and Western blotting (2.5 – 5.0 µg/ml).

Konzentration: 0.25 mg/ml

Reinigung: Prepared by Saturated Ammonium Sulfate (SAS) precipitation

Buffer: 100 µg (0.25 mg/ml) purified rabbit Ig polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

Lagerung: Store at -20°C. Shelf life: 12 months. The antibody solution should be gently mixed before use.

Beschränkungen: Nur für Forschungszwecke einsetzbar