ECM Antikörper

Antigen: ECM

Klonalität: Polyklonal

Wirt: Kaninchen

Reaktivität: Human, Maus, Ratte (Rattus)

Applikation: Western Blot (WB)

Produktnummer: ABIN411477

Produktbeschreibung

Produktmerkmale: 100 ug affinity purified rabbit anti-ECM polyclonal antibody. Reacts with human/mouse/rat. Tested in Western blotting. Other applications have not been determined. Blocking peptide (Cat.# 3843BP-50) is available separately.

Gen-ID: 13601

Immunogen: Synthetic peptide corresponding to residues surrounding amino acids 546 of mouse ECM-1

Isotyp: IgG  (Passende Sekundärantikörper)

Beschreibung: Stearoyl-CoA desaturase (SCD) is a regulatory enzyme involved in the synthesis of oleate and palmitoleate. Oleate and palmitoleate are the main components of membrane phospholipid, triglycerides and cholesterol esters. SCD plays an important role in cellular cholesterol homeostasis and also in the secretion processes of triacylglycerol and phospholipid. Inhibition of SCD could be a useful treatment for metabollic disorders such as obesity and hepatic steatosis.

Anwendungen

Applikationshinweise: Western blotting (0.5-4 µg/ml). However, the optimal conditions should be determined individually. The antibody recognizes ~61 kDa ECM-1 of human, mouse, and rat origins. Reactivity to other species has not been tested.

Konzentration: 0.5 mg/ml

Reinigung: Affinity Purified Antibody

Buffer: 100 µg (0.5 mg/ml) affinity purified rabbit anti-ECM-1 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal.

Lagerung: Store at -20°C. Shelf life: 12 months. The antibody solution should be gently mixed before use.

Beschränkungen: Nur für Forschungszwecke einsetzbar